The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function.
Publication
, Journal Article
Friedman, AH; Marchese, AL
Published in: J Pharmacol Methods
May 1981
The isolated frog eye perfused through its ophthalmic artery with a modified oxygenated Sickel's media responds to light stimuli of different wavelengths in a manner similar to that observed in the frog eye in vivo for periods of 9 hr and longer. Short- and long-duration field potentials from the globe (ERG) and optic nerve (ONP) can be recorded simultaneously. Drugs perfused through the eye can be shown to modify components of the ERG and ONP and to alter the flow rate of the perfusion media through the eye.
Duke Scholars
Published In
J Pharmacol Methods
DOI
ISSN
0160-5402
Publication Date
May 1981
Volume
5
Issue
3
Start / End Page
215 / 234
Location
United States
Related Subject Headings
- Retina
- Rana pipiens
- Rana catesbeiana
- Photic Stimulation
- Perfusion
- Optic Nerve
- Ocular Physiological Phenomena
- Male
- In Vitro Techniques
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Friedman, A. H., & Marchese, A. L. (1981). The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function. J Pharmacol Methods, 5(3), 215–234. https://doi.org/10.1016/0160-5402(81)90089-9
Friedman, A. H., and A. L. Marchese. “The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function.” J Pharmacol Methods 5, no. 3 (May 1981): 215–34. https://doi.org/10.1016/0160-5402(81)90089-9.
Friedman AH, Marchese AL. The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function. J Pharmacol Methods. 1981 May;5(3):215–34.
Friedman, A. H., and A. L. Marchese. “The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function.” J Pharmacol Methods, vol. 5, no. 3, May 1981, pp. 215–34. Pubmed, doi:10.1016/0160-5402(81)90089-9.
Friedman AH, Marchese AL. The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function. J Pharmacol Methods. 1981 May;5(3):215–234.
Published In
J Pharmacol Methods
DOI
ISSN
0160-5402
Publication Date
May 1981
Volume
5
Issue
3
Start / End Page
215 / 234
Location
United States
Related Subject Headings
- Retina
- Rana pipiens
- Rana catesbeiana
- Photic Stimulation
- Perfusion
- Optic Nerve
- Ocular Physiological Phenomena
- Male
- In Vitro Techniques
- Female