Association and chance occurrence of aniridia and retinoblastoma.
Publication
, Journal Article
To, KW; Mukai, S; Friedman, AH
Published in: Am J Ophthalmol
December 15, 1994
PURPOSE/METHODS: A 9-month-old infant had inherited aniridia and unilateral retinoblastoma. Family history disclosed three generations of aniridia; yet there were no instances of retinoblastoma. The coincidental occurrence of retinoblastoma and aniridia is rare. RESULTS/CONCLUSIONS: With DNA probes from within the retinoblastoma gene, we were able to determine that a retinoblastoma-predisposing mutation was not inherited with aniridia in this family. The occurrence of these two diseases in the same individual therefore represents a chance event.
Duke Scholars
Published In
Am J Ophthalmol
DOI
ISSN
0002-9394
Publication Date
December 15, 1994
Volume
118
Issue
6
Start / End Page
820 / 822
Location
United States
Related Subject Headings
- Retinoblastoma
- Ophthalmology & Optometry
- Mutation
- Male
- Infant
- Humans
- Genes, Retinoblastoma
- Eye Neoplasms
- Aniridia
- 1117 Public Health and Health Services
Citation
APA
Chicago
ICMJE
MLA
NLM
To, K. W., Mukai, S., & Friedman, A. H. (1994). Association and chance occurrence of aniridia and retinoblastoma. Am J Ophthalmol, 118(6), 820–822. https://doi.org/10.1016/s0002-9394(14)72571-1
To, K. W., S. Mukai, and A. H. Friedman. “Association and chance occurrence of aniridia and retinoblastoma.” Am J Ophthalmol 118, no. 6 (December 15, 1994): 820–22. https://doi.org/10.1016/s0002-9394(14)72571-1.
To KW, Mukai S, Friedman AH. Association and chance occurrence of aniridia and retinoblastoma. Am J Ophthalmol. 1994 Dec 15;118(6):820–2.
To, K. W., et al. “Association and chance occurrence of aniridia and retinoblastoma.” Am J Ophthalmol, vol. 118, no. 6, Dec. 1994, pp. 820–22. Pubmed, doi:10.1016/s0002-9394(14)72571-1.
To KW, Mukai S, Friedman AH. Association and chance occurrence of aniridia and retinoblastoma. Am J Ophthalmol. 1994 Dec 15;118(6):820–822.
Published In
Am J Ophthalmol
DOI
ISSN
0002-9394
Publication Date
December 15, 1994
Volume
118
Issue
6
Start / End Page
820 / 822
Location
United States
Related Subject Headings
- Retinoblastoma
- Ophthalmology & Optometry
- Mutation
- Male
- Infant
- Humans
- Genes, Retinoblastoma
- Eye Neoplasms
- Aniridia
- 1117 Public Health and Health Services