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Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents.

Publication ,  Journal Article
Chen, J; Saeki, F; Wiley, BJ; Cang, H; Cobb, MJ; Li, Z-Y; Au, L; Zhang, H; Kimmey, MB; Li, X; Xia, Y
Published in: Nano letters
March 2005

Gold nanocages of <40 nm in dimension have been synthesized using the galvanic replacement reaction between Ag nanocubes and HAuCl4 in an aqueous solution. By controlling the molar ratio between Ag and HAuCl4, the gold nanocages could be tuned to display surface plasmon resonance peaks around 800 nm, a wavelength commonly used in optical coherence tomography (OCT) imaging. OCT measurements on phantom samples indicate that these gold nanocages have a moderate scattering cross-section of approximately 8.10 x 10(-16) m2 but a very large absorption cross-section of approximately 7.26 x 10(-15) m2, suggesting their potential use as a new class of contrast agents for optical imaging. When bioconjugated with antibodies, the gold nanocages have also been demonstrated for specific targeting of breast cancer cells.

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Published In

Nano letters

DOI

EISSN

1530-6992

ISSN

1530-6984

Publication Date

March 2005

Volume

5

Issue

3

Start / End Page

473 / 477

Related Subject Headings

  • Tomography, Optical Coherence
  • Surface Plasmon Resonance
  • Phantoms, Imaging
  • Particle Size
  • Neoplasms
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Materials Testing
  • Immunoassay
  • Humans
 

Citation

APA
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MLA
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Chen, J., Saeki, F., Wiley, B. J., Cang, H., Cobb, M. J., Li, Z.-Y., … Xia, Y. (2005). Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents. Nano Letters, 5(3), 473–477. https://doi.org/10.1021/nl047950t
Chen, Jingyi, Fusayo Saeki, Benjamin J. Wiley, Hu Cang, Michael J. Cobb, Zhi-Yuan Li, Leslie Au, et al. “Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents.Nano Letters 5, no. 3 (March 2005): 473–77. https://doi.org/10.1021/nl047950t.
Chen J, Saeki F, Wiley BJ, Cang H, Cobb MJ, Li Z-Y, et al. Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents. Nano letters. 2005 Mar;5(3):473–7.
Chen, Jingyi, et al. “Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents.Nano Letters, vol. 5, no. 3, Mar. 2005, pp. 473–77. Epmc, doi:10.1021/nl047950t.
Chen J, Saeki F, Wiley BJ, Cang H, Cobb MJ, Li Z-Y, Au L, Zhang H, Kimmey MB, Li X, Xia Y. Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents. Nano letters. 2005 Mar;5(3):473–477.
Journal cover image

Published In

Nano letters

DOI

EISSN

1530-6992

ISSN

1530-6984

Publication Date

March 2005

Volume

5

Issue

3

Start / End Page

473 / 477

Related Subject Headings

  • Tomography, Optical Coherence
  • Surface Plasmon Resonance
  • Phantoms, Imaging
  • Particle Size
  • Neoplasms
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Materials Testing
  • Immunoassay
  • Humans