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Takayasu's arteritis: assessment of disease activity with contrast-enhanced MR imaging.

Publication ,  Journal Article
Choe, YH; Han, BK; Koh, EM; Kim, DK; Do, YS; Lee, WR
Published in: AJR Am J Roentgenol
August 2000

OBJECTIVE: The purpose of this study was to evaluate the role of contrast-enhanced MR imaging in the determination of disease activity in patients with Takayasu's arteritis. SUBJECTS AND METHODS: High-resolution contrast-enhanced T1-weighted spinecho MR imaging using small fields of view (14-20 cm) and thin slices (4-5 mm) was performed in 26 patients with Takayasu's arteritis and 16 healthy subjects. The degree of aortic mural enhancement was assessed by measuring signal intensity and by visually estimating it in comparison with that of the myocardium. RESULTS: Contrast-enhanced MR imaging showed more enhancement of thickened aortic wall compared with myocardium, thus suggesting active Takayasu's arteritis on MR imaging in 16 patients. Determination of disease activity using contrast-enhanced MR imaging was concordant with clinical findings in 23 patients (88.5%). Contrast-enhanced MR findings were concordant with laboratory findings in most patients (erythrocyte sedimentation rate in 92.3% [24/26] and C-reactive protein in 84.6% [22/26]). The measured signal intensity of the aortic wall relative to that of myocardium during the early phase of contrast-enhanced MR imaging correlated well with the erythrocyte sedimentation rate (r = 0.78, p < 0.005) and with the C-reactive protein level (r = 0.63, p < 0.005). CONCLUSION: Contrast-enhanced MR imaging provides information about disease activity of Takayasu's arteritis, which may be useful in the diagnosis and treatment of Takayasu's arteritis.

Duke Scholars

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

August 2000

Volume

175

Issue

2

Start / End Page

505 / 511

Location

United States

Related Subject Headings

  • Takayasu Arteritis
  • Prospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Image Enhancement
  • Humans
  • Female
  • Child, Preschool
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Choe, Y. H., Han, B. K., Koh, E. M., Kim, D. K., Do, Y. S., & Lee, W. R. (2000). Takayasu's arteritis: assessment of disease activity with contrast-enhanced MR imaging. AJR Am J Roentgenol, 175(2), 505–511. https://doi.org/10.2214/ajr.175.2.1750505
Choe, Y. H., B. K. Han, E. M. Koh, D. K. Kim, Y. S. Do, and W. R. Lee. “Takayasu's arteritis: assessment of disease activity with contrast-enhanced MR imaging.AJR Am J Roentgenol 175, no. 2 (August 2000): 505–11. https://doi.org/10.2214/ajr.175.2.1750505.
Choe YH, Han BK, Koh EM, Kim DK, Do YS, Lee WR. Takayasu's arteritis: assessment of disease activity with contrast-enhanced MR imaging. AJR Am J Roentgenol. 2000 Aug;175(2):505–11.
Choe, Y. H., et al. “Takayasu's arteritis: assessment of disease activity with contrast-enhanced MR imaging.AJR Am J Roentgenol, vol. 175, no. 2, Aug. 2000, pp. 505–11. Pubmed, doi:10.2214/ajr.175.2.1750505.
Choe YH, Han BK, Koh EM, Kim DK, Do YS, Lee WR. Takayasu's arteritis: assessment of disease activity with contrast-enhanced MR imaging. AJR Am J Roentgenol. 2000 Aug;175(2):505–511.

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

August 2000

Volume

175

Issue

2

Start / End Page

505 / 511

Location

United States

Related Subject Headings

  • Takayasu Arteritis
  • Prospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Image Enhancement
  • Humans
  • Female
  • Child, Preschool