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Within- and between- subject variability of indices from the closing volume and flow volume traces.

Publication ,  Journal Article
Chinn, DJ; Lee, WR
Published in: Bulletin européen de physiopathologie respiratoire,
1977

The within-subject variability of consecutive measurements of indices derived from the closing volume (CV) trace and from the maximal expiratory flow volume (MEFV) curve was studied in 24 subjects. The variability of the closing volume and of the maximal expiratory flow rates at 50 percent (Vmax. 50) and 75 percent (Vmax. 75) of the expired vital capacity was about three to eight times greater than that of the FEV1, FVC or FEV1 percent. The lung volume measured from total lung capacity to the onset of airway closure (OAC) was about five times more reproducible than the CV. The coefficients of variation for the CV (as a percentage of the vital capacity), the Vmax. 75, and the OAC, both in litres and as a percentage of the vital capacity, were significantly correlated with age. No difference in the mean coefficients of variation for the CV, OAC, Vmax. 50 or Vmax. 75 were found with respect to sex, smoking habit or previous experience with the test routines. The between-subject variability of the FEV1, FVC, FEV1 percent, transfer factor, diffusion coefficient, Vmax. 50, Vmax. 75, CV and OAC was evaluated from a study of 75 asymptomatic lifetime non-smokers. The variability of the Vmax. 50, Vmax. 75 and CV was about two to eight times greater than that of the other tests used, irrespective of sex. The OAC (percent VC) was three to four times less variable than the CV. The variability of the Vmax. 50 and Vmax. 75 was reduced by, on average, 7 percent when these flow rates were expressed per litre of FVC.

Published In

Bulletin européen de physiopathologie respiratoire,

ISSN

0395-3890

Publication Date

1977

Volume

13

Issue

6

Start / End Page

789 / 802

Location

france

Related Subject Headings

  • Vital Capacity
  • Reference Values
  • Pulmonary Ventilation
  • Middle Aged
  • Maximal Expiratory Flow Rate
  • Male
  • Lung Volume Measurements
  • Humans
  • Genetic Variation
  • Forced Expiratory Volume
 

Citation

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MLA
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Chinn, D. J., & Lee, W. R. (1977). Within- and between- subject variability of indices from the closing volume and flow volume traces. Bulletin Européen de Physiopathologie Respiratoire, 13(6), 789–802.
Chinn, D. J., and W. R. Lee. “Within- and between- subject variability of indices from the closing volume and flow volume traces.Bulletin Européen de Physiopathologie Respiratoire, 13, no. 6 (1977): 789–802.
Chinn DJ, Lee WR. Within- and between- subject variability of indices from the closing volume and flow volume traces. Bulletin européen de physiopathologie respiratoire,. 1977;13(6):789–802.
Chinn, D. J., and W. R. Lee. “Within- and between- subject variability of indices from the closing volume and flow volume traces.Bulletin Européen de Physiopathologie Respiratoire, vol. 13, no. 6, 1977, pp. 789–802.
Chinn DJ, Lee WR. Within- and between- subject variability of indices from the closing volume and flow volume traces. Bulletin européen de physiopathologie respiratoire,. 1977;13(6):789–802.

Published In

Bulletin européen de physiopathologie respiratoire,

ISSN

0395-3890

Publication Date

1977

Volume

13

Issue

6

Start / End Page

789 / 802

Location

france

Related Subject Headings

  • Vital Capacity
  • Reference Values
  • Pulmonary Ventilation
  • Middle Aged
  • Maximal Expiratory Flow Rate
  • Male
  • Lung Volume Measurements
  • Humans
  • Genetic Variation
  • Forced Expiratory Volume