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Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology.

Publication ,  Journal Article
Davidson, CJ; Sheikh, KH; Harrison, JK; Himmelstein, SI; Leithe, ME; Kisslo, KB; Bashore, TM
Published in: J Am Coll Cardiol
September 1990

The accuracy of catheter-based intravascular ultrasonography to define luminal size in humans in vivo and its sensitivity to describe lesion morphology have not been previously reported. Vessel diameter, cross-sectional area and lesion characteristics assessed by digital subtraction angiography and intravascular ultrasonography (20 MHz) were compared in 86 human arterial segments. The same arterial segments were imaged and analyzed by digital subtraction angiography and intravascular ultrasonography at 49 femoral, 3 renal, 5 iliac, 7 pulmonary and 22 aortic sites. Digital subtraction angiographic diameter and area were determined geometrically by an automated algorithm. Intravascular ultrasonographic diameter and area were determined by planimetry. Linear correlation for diameter by the two techniques was 0.97, standard error of the estimate (SEE) = 1.83 mm, and for cross-sectional area it was 0.95, SEE = 0.65 cm2. Intravascular ultrasonography identified 24 sites in which plaque was present; 11 (46%) of these segments appeared normal by digital subtraction angiography. Conversely, digital subtraction angiography demonstrated irregularities in 18 segments of which 5 (28%) appeared normal by intravascular ultrasonography. These data indicate an excellent correlation between intravascular ultrasonography and digital subtraction angiography for in vivo assessment of human arterial dimensions in normal and minimally diseased segments. However, intravascular ultrasonography is more likely to identify atherosclerotic plaque that may be angiographically "silent."

Duke Scholars

Published In

J Am Coll Cardiol

DOI

ISSN

0735-1097

Publication Date

September 1990

Volume

16

Issue

3

Start / End Page

633 / 636

Location

United States

Related Subject Headings

  • Ultrasonography
  • Renal Artery
  • Pulmonary Artery
  • Middle Aged
  • Male
  • Iliac Artery
  • Humans
  • Femoral Artery
  • Female
  • Cardiovascular System & Hematology
 

Citation

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Davidson, C. J., Sheikh, K. H., Harrison, J. K., Himmelstein, S. I., Leithe, M. E., Kisslo, K. B., & Bashore, T. M. (1990). Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology. J Am Coll Cardiol, 16(3), 633–636. https://doi.org/10.1016/0735-1097(90)90354-r
Davidson, C. J., K. H. Sheikh, J. K. Harrison, S. I. Himmelstein, M. E. Leithe, K. B. Kisslo, and T. M. Bashore. “Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology.J Am Coll Cardiol 16, no. 3 (September 1990): 633–36. https://doi.org/10.1016/0735-1097(90)90354-r.
Davidson CJ, Sheikh KH, Harrison JK, Himmelstein SI, Leithe ME, Kisslo KB, et al. Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology. J Am Coll Cardiol. 1990 Sep;16(3):633–6.
Davidson, C. J., et al. “Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology.J Am Coll Cardiol, vol. 16, no. 3, Sept. 1990, pp. 633–36. Pubmed, doi:10.1016/0735-1097(90)90354-r.
Davidson CJ, Sheikh KH, Harrison JK, Himmelstein SI, Leithe ME, Kisslo KB, Bashore TM. Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology. J Am Coll Cardiol. 1990 Sep;16(3):633–636.
Journal cover image

Published In

J Am Coll Cardiol

DOI

ISSN

0735-1097

Publication Date

September 1990

Volume

16

Issue

3

Start / End Page

633 / 636

Location

United States

Related Subject Headings

  • Ultrasonography
  • Renal Artery
  • Pulmonary Artery
  • Middle Aged
  • Male
  • Iliac Artery
  • Humans
  • Femoral Artery
  • Female
  • Cardiovascular System & Hematology