Skip to main content
Journal cover image

Posttraumatic abducens to oculomotor nerve misdirection.

Publication ,  Journal Article
Buckley, EG; Ellis, FD; Postel, E; Saunders, T
Published in: J AAPOS
February 2005

INTRODUCTION: Paradoxical patterns of extraocular muscle, eyelid, or pupillary movements can occur following injury between divisions of the oculomotor nerve, trigeminal and abducens nerves, and trigeminal and oculomotor nerves. We report three cases of unusual ocular motility and eyelid movements that are a result of aberrant connections between the abducens and oculomotor nerves. METHODS: Three patients with unusual eye movement abnormalities after trauma were studied. A complete ophthalmic examination plus neuroradiologic evaluation were performed. RESULTS: Each patient manifested an aberrant connection between the 6th and 3rd cranial nerves resulting in third nerve function during sixth nerve stimulation. Two patients demonstrated complete third nerve palsies except for adduction on attempted abduction. The third showed improved bilateral ptosis on abduction. CONCLUSIONS: The neuroanatomical abnormalities involve intraorbital structures in one patient and central nervous system pathways in the others. Explanations such as retrograde regeneration, ephaptic transmission, or denervation supersensitivity do not appear to explain these unusual eye movements. The most likely mechanism involves some form of peripheral neuronal misdirection. These rare sixth to third nerve misdirection cases add support to the "neuronal misdirection hypothesis" of aberrant eye movements after trauma.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J AAPOS

DOI

ISSN

1091-8531

Publication Date

February 2005

Volume

9

Issue

1

Start / End Page

12 / 16

Location

United States

Related Subject Headings

  • Pupil Disorders
  • Orbit
  • Ophthalmoplegia
  • Ophthalmology & Optometry
  • Oculomotor Nerve Injuries
  • Oculomotor Nerve
  • Nerve Regeneration
  • Male
  • Humans
  • Head Injuries, Closed
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Buckley, E. G., Ellis, F. D., Postel, E., & Saunders, T. (2005). Posttraumatic abducens to oculomotor nerve misdirection. J AAPOS, 9(1), 12–16. https://doi.org/10.1016/j.jaapos.2004.11.011
Buckley, Edward G., Forrest D. Ellis, Eric Postel, and Timothy Saunders. “Posttraumatic abducens to oculomotor nerve misdirection.J AAPOS 9, no. 1 (February 2005): 12–16. https://doi.org/10.1016/j.jaapos.2004.11.011.
Buckley EG, Ellis FD, Postel E, Saunders T. Posttraumatic abducens to oculomotor nerve misdirection. J AAPOS. 2005 Feb;9(1):12–6.
Buckley, Edward G., et al. “Posttraumatic abducens to oculomotor nerve misdirection.J AAPOS, vol. 9, no. 1, Feb. 2005, pp. 12–16. Pubmed, doi:10.1016/j.jaapos.2004.11.011.
Buckley EG, Ellis FD, Postel E, Saunders T. Posttraumatic abducens to oculomotor nerve misdirection. J AAPOS. 2005 Feb;9(1):12–16.
Journal cover image

Published In

J AAPOS

DOI

ISSN

1091-8531

Publication Date

February 2005

Volume

9

Issue

1

Start / End Page

12 / 16

Location

United States

Related Subject Headings

  • Pupil Disorders
  • Orbit
  • Ophthalmoplegia
  • Ophthalmology & Optometry
  • Oculomotor Nerve Injuries
  • Oculomotor Nerve
  • Nerve Regeneration
  • Male
  • Humans
  • Head Injuries, Closed