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Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse.

Publication ,  Journal Article
Colton, CA; Colton, JS; Gilbert, DL
Published in: Comp Biochem Physiol Comp Physiol
June 1992

1. Synaptic transmission at the squid giant synapse was blocked in 45 min by exposure to 0.02 atm oxygen but was maintained for more than 90 min in air (0.21 atm oxygen) or pure oxygen (1 atm). 2. Excitatory post-synaptic potential amplitude decreased in 0.02 atm oxygen but did not change in either 1 or 0.21 atm oxygen. Fast facilitation was increased in 0.02 atm oxygen only. 3. Post-synaptic resting membrane potential (Vm) and input resistance (Ro) remained unchanged in 1 or 0.21 atm oxygen but Ro was increased in 0.02 atm oxygen. 4. Our results suggest that severe hypoxia decreased the release of transmitter from the pre-synaptic terminal.

Duke Scholars

Published In

Comp Biochem Physiol Comp Physiol

DOI

Publication Date

June 1992

Volume

102

Issue

2

Start / End Page

279 / 283

Location

England

Related Subject Headings

  • Synaptic Transmission
  • Synapses
  • Oxygen
  • Membrane Potentials
  • Decapodiformes
  • Cells, Cultured
  • Cell Hypoxia
  • Animals
 

Citation

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Chicago
ICMJE
MLA
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Colton, C. A., Colton, J. S., & Gilbert, D. L. (1992). Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse. Comp Biochem Physiol Comp Physiol, 102(2), 279–283. https://doi.org/10.1016/0300-9629(92)90135-d
Colton, C. A., J. S. Colton, and D. L. Gilbert. “Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse.Comp Biochem Physiol Comp Physiol 102, no. 2 (June 1992): 279–83. https://doi.org/10.1016/0300-9629(92)90135-d.
Colton CA, Colton JS, Gilbert DL. Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse. Comp Biochem Physiol Comp Physiol. 1992 Jun;102(2):279–83.
Colton, C. A., et al. “Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse.Comp Biochem Physiol Comp Physiol, vol. 102, no. 2, June 1992, pp. 279–83. Pubmed, doi:10.1016/0300-9629(92)90135-d.
Colton CA, Colton JS, Gilbert DL. Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse. Comp Biochem Physiol Comp Physiol. 1992 Jun;102(2):279–283.

Published In

Comp Biochem Physiol Comp Physiol

DOI

Publication Date

June 1992

Volume

102

Issue

2

Start / End Page

279 / 283

Location

England

Related Subject Headings

  • Synaptic Transmission
  • Synapses
  • Oxygen
  • Membrane Potentials
  • Decapodiformes
  • Cells, Cultured
  • Cell Hypoxia
  • Animals