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Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis.

Publication ,  Journal Article
Syn, W-K; Teaberry, V; Choi, SS; Diehl, AM
Published in: Semin Liver Dis
May 2009

Subpopulations of individuals with alcohol-induced fatty livers and nonalcoholic steatosis develop steatohepatitis. Steatohepatitis is defined histologically: increased numbers of injured and dying hepatocytes distinguish this condition from simple steatosis. The increased hepatocyte death is generally accompanied by hepatic accumulation of inflammatory cells and sometimes increases in myofibroblastic cells, leading to hepatic fibrosis and eventually, cirrhosis. The purpose of this review is to summarize similarities and differences in the pathogenesis of steatohepatitis in alcoholic fatty liver disease and nonalcoholic fatty liver disease.

Duke Scholars

Published In

Semin Liver Dis

DOI

EISSN

1098-8971

Publication Date

May 2009

Volume

29

Issue

2

Start / End Page

200 / 210

Location

United States

Related Subject Headings

  • Risk Factors
  • Oxidative Stress
  • Lipid Metabolism
  • Inflammation Mediators
  • Humans
  • Hepatocytes
  • Gastrointestinal Tract
  • Gastroenterology & Hepatology
  • Fatty Liver, Alcoholic
  • Fatty Liver
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Syn, W.-K., Teaberry, V., Choi, S. S., & Diehl, A. M. (2009). Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. Semin Liver Dis, 29(2), 200–210. https://doi.org/10.1055/s-0029-1214375
Syn, Wing-Kin, Vanessa Teaberry, Steve S. Choi, and Anna Mae Diehl. “Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis.Semin Liver Dis 29, no. 2 (May 2009): 200–210. https://doi.org/10.1055/s-0029-1214375.
Syn W-K, Teaberry V, Choi SS, Diehl AM. Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. Semin Liver Dis. 2009 May;29(2):200–10.
Syn, Wing-Kin, et al. “Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis.Semin Liver Dis, vol. 29, no. 2, May 2009, pp. 200–10. Pubmed, doi:10.1055/s-0029-1214375.
Syn W-K, Teaberry V, Choi SS, Diehl AM. Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. Semin Liver Dis. 2009 May;29(2):200–210.
Journal cover image

Published In

Semin Liver Dis

DOI

EISSN

1098-8971

Publication Date

May 2009

Volume

29

Issue

2

Start / End Page

200 / 210

Location

United States

Related Subject Headings

  • Risk Factors
  • Oxidative Stress
  • Lipid Metabolism
  • Inflammation Mediators
  • Humans
  • Hepatocytes
  • Gastrointestinal Tract
  • Gastroenterology & Hepatology
  • Fatty Liver, Alcoholic
  • Fatty Liver