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Variation of neutrophil function with age in calves.

Publication ,  Journal Article
Hauser, MA; Koob, MD; Roth, JA
Published in: American journal of veterinary research
January 1986

Neutrophil function was evaluated on 2 occasions in 5 calves from each of the following age groups: 4 to 5 weeks, 9 to 11 weeks, 16 to 19 weeks, and 12 to 14 months. Of the neutrophil functions examined, the iodination reaction, which evaluates the activity of the myeloperoxidase-hydrogen peroxide-halide antibacterial system of the neutrophil, reflected the most marked differences among age groups. The iodination values for the 2 youngest age groups were approximately 52% of the value for the oldest cattle. This difference could not be attributed to the amount of myeloperoxidase in the neutrophil granules. Antibody-dependent cell-mediated cytotoxicity also tended to be lower in neutrophils from the 3 younger age groups. Nitroblue tetrazolium reduction, a measure of superoxide anion generation by neutrophils, was lower in the youngest age group only. The capability of neutrophils to ingest Staphylococcus aureus was higher in the 3 youngest groups of calves than in the oldest group. The observed differences in neutrophil function in young vs older calves may be partially responsible for the increased susceptibility of young calves to infectious disease.

Duke Scholars

Published In

American journal of veterinary research

ISSN

0002-9645

Publication Date

January 1986

Volume

47

Issue

1

Start / End Page

152 / 153

Location

united states

Related Subject Headings

  • Veterinary Sciences
  • 07 Agricultural and Veterinary Sciences
  • 06 Biological Sciences
 

Citation

APA
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ICMJE
MLA
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Hauser, M. A., Koob, M. D., & Roth, J. A. (1986). Variation of neutrophil function with age in calves. American Journal of Veterinary Research, 47(1), 152–153.
Hauser, M. A., M. D. Koob, and J. A. Roth. “Variation of neutrophil function with age in calves.American Journal of Veterinary Research 47, no. 1 (January 1986): 152–53.
Hauser MA, Koob MD, Roth JA. Variation of neutrophil function with age in calves. American journal of veterinary research. 1986 Jan;47(1):152–3.
Hauser, M. A., et al. “Variation of neutrophil function with age in calves.American Journal of Veterinary Research, vol. 47, no. 1, Jan. 1986, pp. 152–53.
Hauser MA, Koob MD, Roth JA. Variation of neutrophil function with age in calves. American journal of veterinary research. 1986 Jan;47(1):152–153.

Published In

American journal of veterinary research

ISSN

0002-9645

Publication Date

January 1986

Volume

47

Issue

1

Start / End Page

152 / 153

Location

united states

Related Subject Headings

  • Veterinary Sciences
  • 07 Agricultural and Veterinary Sciences
  • 06 Biological Sciences