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Molecular genetics of human myopia: an update.

Publication ,  Journal Article
Young, TL
Published in: Optom Vis Sci
January 2009

Myopia, or nearsightedness, is the most common human eye disorder in the world, and is a significant global public health concern. Along with cataract, macular degeneration, infectious disease, and vitamin A deficiency, myopia is one of the most important causes of visual impairment worldwide. Severe or high-grade myopia is a leading cause of blindness because of its associated ocular morbidities of retinal detachment, macular choroidal degeneration, premature cataract, and glaucoma. Ample evidence documents the heritability of the non-syndromic forms of this condition, especially for high-grade myopia, commonly referred to as myopic spherical refractive power of 5 to 6 diopters or higher. Multiple high-grade myopia genetic loci have been identified, and confirmatory studies identifying high-grade and moderate myopia loci have also occurred. In general, myopia susceptibility genes are unknown with few association studies performed, and without confirmation in other research laboratories or testing of separate patient cohorts.

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Published In

Optom Vis Sci

DOI

EISSN

1538-9235

Publication Date

January 2009

Volume

86

Issue

1

Start / End Page

E8 / E22

Location

United States

Related Subject Headings

  • Risk Factors
  • Research
  • Ophthalmology & Optometry
  • Ocular Physiological Phenomena
  • Myopia
  • Molecular Biology
  • Longitudinal Studies
  • Humans
  • Eye
  • Education
 

Citation

APA
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ICMJE
MLA
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Young, T. L. (2009). Molecular genetics of human myopia: an update. Optom Vis Sci, 86(1), E8–E22. https://doi.org/10.1097/OPX.0b013e3181940655
Young, Terri L. “Molecular genetics of human myopia: an update.Optom Vis Sci 86, no. 1 (January 2009): E8–22. https://doi.org/10.1097/OPX.0b013e3181940655.
Young TL. Molecular genetics of human myopia: an update. Optom Vis Sci. 2009 Jan;86(1):E8–22.
Young, Terri L. “Molecular genetics of human myopia: an update.Optom Vis Sci, vol. 86, no. 1, Jan. 2009, pp. E8–22. Pubmed, doi:10.1097/OPX.0b013e3181940655.
Young TL. Molecular genetics of human myopia: an update. Optom Vis Sci. 2009 Jan;86(1):E8–E22.

Published In

Optom Vis Sci

DOI

EISSN

1538-9235

Publication Date

January 2009

Volume

86

Issue

1

Start / End Page

E8 / E22

Location

United States

Related Subject Headings

  • Risk Factors
  • Research
  • Ophthalmology & Optometry
  • Ocular Physiological Phenomena
  • Myopia
  • Molecular Biology
  • Longitudinal Studies
  • Humans
  • Eye
  • Education