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In vivo visualization of abdominal malignancies with acoustic radiation force elastography.

Publication ,  Journal Article
Fahey, BJ; Nelson, RC; Bradway, DP; Hsu, SJ; Dumont, DM; Trahey, GE
Published in: Phys Med Biol
January 7, 2008

The utility of acoustic radiation force impulse (ARFI) imaging for real-time visualization of abdominal malignancies was investigated. Nine patients presenting with suspicious masses in the liver (n = 7) or kidney (n = 2) underwent combined sonography/ARFI imaging. Images were acquired of a total of 12 tumors in the nine patients. In all cases, boundary definition in ARFI images was improved or equivalent to boundary definition in B-mode images. Displacement contrast in ARFI images was superior to echo contrast in B-mode images for each tumor. The mean contrast for suspected hepatocellular carcinomas (HCCs) in B-mode images was 2.9 dB (range: 1.5-4.2) versus 7.5 dB (range: 3.1-11.9) in ARFI images, with all HCCs appearing more compliant than regional cirrhotic liver parenchyma. The mean contrast for metastases in B-mode images was 3.1 dB (range: 1.2-5.2) versus 9.3 dB (range: 5.7-13.9) in ARFI images, with all masses appearing less compliant than regional non-cirrhotic liver parenchyma. ARFI image contrast (10.4 dB) was superior to B-mode contrast (0.9 dB) for a renal mass. To our knowledge, we present the first in vivo images of abdominal malignancies in humans acquired with the ARFI method or any other technique of imaging tissue elasticity.

Duke Scholars

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

January 7, 2008

Volume

53

Issue

1

Start / End Page

279 / 293

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Kidney Neoplasms
  • Humans
  • Female
  • Elasticity Imaging Techniques
  • Carcinoma, Hepatocellular
 

Citation

APA
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Fahey, B. J., Nelson, R. C., Bradway, D. P., Hsu, S. J., Dumont, D. M., & Trahey, G. E. (2008). In vivo visualization of abdominal malignancies with acoustic radiation force elastography. Phys Med Biol, 53(1), 279–293. https://doi.org/10.1088/0031-9155/53/1/020
Fahey, B. J., R. C. Nelson, D. P. Bradway, S. J. Hsu, D. M. Dumont, and G. E. Trahey. “In vivo visualization of abdominal malignancies with acoustic radiation force elastography.Phys Med Biol 53, no. 1 (January 7, 2008): 279–93. https://doi.org/10.1088/0031-9155/53/1/020.
Fahey BJ, Nelson RC, Bradway DP, Hsu SJ, Dumont DM, Trahey GE. In vivo visualization of abdominal malignancies with acoustic radiation force elastography. Phys Med Biol. 2008 Jan 7;53(1):279–93.
Fahey, B. J., et al. “In vivo visualization of abdominal malignancies with acoustic radiation force elastography.Phys Med Biol, vol. 53, no. 1, Jan. 2008, pp. 279–93. Pubmed, doi:10.1088/0031-9155/53/1/020.
Fahey BJ, Nelson RC, Bradway DP, Hsu SJ, Dumont DM, Trahey GE. In vivo visualization of abdominal malignancies with acoustic radiation force elastography. Phys Med Biol. 2008 Jan 7;53(1):279–293.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

January 7, 2008

Volume

53

Issue

1

Start / End Page

279 / 293

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Kidney Neoplasms
  • Humans
  • Female
  • Elasticity Imaging Techniques
  • Carcinoma, Hepatocellular