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Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit.

Publication ,  Journal Article
Hida, T; Sheta, SM; Proia, AD; McCuen, BW
Published in: Retina
1988

N-butyl-2-cyanoacrylate tissue adhesive was injected into the preretinal space of rabbit eyes to study potential toxicity to the retina. Application of 3.3-10.0 ul of cyanoacrylate tissue adhesive showed localized but definite retinal toxicity. White halos appeared surrounding the preretinal cyanoacrylate immediately after injection with a gradual evolution of the white areas into pigmentary scars by 1 month. Histological examination confirmed severe focal necrosis of the retina. No identifiable distant toxic effects or electrophysiologic changes were observed during the 6-month follow-up period.

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Published In

Retina

DOI

ISSN

0275-004X

Publication Date

1988

Volume

8

Issue

2

Start / End Page

148 / 153

Location

United States

Related Subject Headings

  • Tissue Adhesives
  • Retina
  • Ophthalmology & Optometry
  • Necrosis
  • Follow-Up Studies
  • Electroretinography
  • Cyanoacrylates
  • Body Temperature
  • Animals
  • 3212 Ophthalmology and optometry
 

Citation

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Hida, T., Sheta, S. M., Proia, A. D., & McCuen, B. W. (1988). Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit. Retina, 8(2), 148–153. https://doi.org/10.1097/00006982-198808020-00013
Hida, T., S. M. Sheta, A. D. Proia, and B. W. McCuen. “Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit.Retina 8, no. 2 (1988): 148–53. https://doi.org/10.1097/00006982-198808020-00013.
Hida T, Sheta SM, Proia AD, McCuen BW. Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit. Retina. 1988;8(2):148–53.
Hida, T., et al. “Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit.Retina, vol. 8, no. 2, 1988, pp. 148–53. Pubmed, doi:10.1097/00006982-198808020-00013.
Hida T, Sheta SM, Proia AD, McCuen BW. Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit. Retina. 1988;8(2):148–153.

Published In

Retina

DOI

ISSN

0275-004X

Publication Date

1988

Volume

8

Issue

2

Start / End Page

148 / 153

Location

United States

Related Subject Headings

  • Tissue Adhesives
  • Retina
  • Ophthalmology & Optometry
  • Necrosis
  • Follow-Up Studies
  • Electroretinography
  • Cyanoacrylates
  • Body Temperature
  • Animals
  • 3212 Ophthalmology and optometry