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Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship.

Publication ,  Journal Article
Akita, S; Sacks, FM; Svetkey, LP; Conlin, PR; Kimura, G; DASH-Sodium Trial Collaborative Research Group,
Published in: Hypertension
July 2003

Blood pressure-lowering mechanisms of the Dietary Approaches to Stop Hypertension (DASH) diet, rich in fruits, vegetables, and low-fat dairy foods, were analyzed based on the pressure-natriuresis relationship. Participants (n=375) were randomly assigned to control or DASH diet groups by using a parallel-group design. They then ate their assigned diet for 3 consecutive 30-day intervention feeding periods, during which sodium intake varied among 3 levels by a randomly assigned sequence. Urinary sodium excretion rate and mean arterial pressure were measured at the end of each sodium intake level. Mean arterial pressure and urinary sodium excretion were plotted on x and y axes, respectively, for participants eating control and DASH diets and were modeled as linear relationships for simplicity to allow the estimation of the extrapolated x-intercept and slope of the relationships. The DASH diet steepened the slope of the relationship (29.5+/-3.4 vs 64.9+/-13.1 [mmol/d]/mm Hg, P=0.0002) without significantly shifting the x-intercept (94.1+/-0.5 vs 93.2+/-0.6 mm Hg, NS) of the relationship. These data suggest a natriuretic action of the DASH diet.

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Published In

Hypertension

DOI

EISSN

1524-4563

Publication Date

July 2003

Volume

42

Issue

1

Start / End Page

8 / 13

Location

United States

Related Subject Headings

  • Sodium
  • Natriuresis
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Female
  • Cardiovascular System & Hematology
  • Blood Pressure
  • Adult
 

Citation

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Akita, S., Sacks, F. M., Svetkey, L. P., Conlin, P. R., Kimura, G., & DASH-Sodium Trial Collaborative Research Group, . (2003). Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship. Hypertension, 42(1), 8–13. https://doi.org/10.1161/01.HYP.0000074668.08704.6E
Akita, Sachie, Frank M. Sacks, Laura P. Svetkey, Paul R. Conlin, Genjiro Kimura, and Genjiro DASH-Sodium Trial Collaborative Research Group. “Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship.Hypertension 42, no. 1 (July 2003): 8–13. https://doi.org/10.1161/01.HYP.0000074668.08704.6E.
Akita S, Sacks FM, Svetkey LP, Conlin PR, Kimura G, DASH-Sodium Trial Collaborative Research Group. Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship. Hypertension. 2003 Jul;42(1):8–13.
Akita, Sachie, et al. “Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship.Hypertension, vol. 42, no. 1, July 2003, pp. 8–13. Pubmed, doi:10.1161/01.HYP.0000074668.08704.6E.
Akita S, Sacks FM, Svetkey LP, Conlin PR, Kimura G, DASH-Sodium Trial Collaborative Research Group. Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship. Hypertension. 2003 Jul;42(1):8–13.

Published In

Hypertension

DOI

EISSN

1524-4563

Publication Date

July 2003

Volume

42

Issue

1

Start / End Page

8 / 13

Location

United States

Related Subject Headings

  • Sodium
  • Natriuresis
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Female
  • Cardiovascular System & Hematology
  • Blood Pressure
  • Adult