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IDH1 and IDH2: not your typical oncogenes.

Publication ,  Journal Article
Reitman, ZJ; Parsons, DW; Yan, H
Published in: Cancer Cell
March 16, 2010

Oncogenes usually increase their normal function when activated. However, seemingly oncogenic mutations in IDH1 and IDH2 reduce their native enzyme activity. In this issue of Cancer Cell, Ward et al. pin down a neomorphic enzyme activity as a possible oncogenic function for these alterations.

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Published In

Cancer Cell

DOI

EISSN

1878-3686

Publication Date

March 16, 2010

Volume

17

Issue

3

Start / End Page

215 / 216

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • 3211 Oncology and carcinogenesis
  • 3101 Biochemistry and cell biology
  • 1112 Oncology and Carcinogenesis
  • 1109 Neurosciences
 

Citation

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ICMJE
MLA
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Reitman, Z. J., Parsons, D. W., & Yan, H. (2010). IDH1 and IDH2: not your typical oncogenes. Cancer Cell, 17(3), 215–216. https://doi.org/10.1016/j.ccr.2010.02.024
Reitman, Zachary J., D Williams Parsons, and Hai Yan. “IDH1 and IDH2: not your typical oncogenes.Cancer Cell 17, no. 3 (March 16, 2010): 215–16. https://doi.org/10.1016/j.ccr.2010.02.024.
Reitman ZJ, Parsons DW, Yan H. IDH1 and IDH2: not your typical oncogenes. Cancer Cell. 2010 Mar 16;17(3):215–6.
Reitman, Zachary J., et al. “IDH1 and IDH2: not your typical oncogenes.Cancer Cell, vol. 17, no. 3, Mar. 2010, pp. 215–16. Pubmed, doi:10.1016/j.ccr.2010.02.024.
Reitman ZJ, Parsons DW, Yan H. IDH1 and IDH2: not your typical oncogenes. Cancer Cell. 2010 Mar 16;17(3):215–216.
Journal cover image

Published In

Cancer Cell

DOI

EISSN

1878-3686

Publication Date

March 16, 2010

Volume

17

Issue

3

Start / End Page

215 / 216

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • 3211 Oncology and carcinogenesis
  • 3101 Biochemistry and cell biology
  • 1112 Oncology and Carcinogenesis
  • 1109 Neurosciences