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National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000.

Publication ,  Journal Article
Snydman, DR; Jacobus, NV; McDermott, LA; Ruthazer, R; Goldstein, EJC; Finegold, SM; Harrell, LJ; Hecht, DW; Jenkins, SG; Pierson, C; Venezia, R ...
Published in: Clin Infect Dis
September 1, 2002

The results of a multicenter US survey using the National Committee for Clinical Laboratory Standards currently recommended methodology for measuring in vitro susceptibility of 2673 isolates of Bacteroides fragilis group species were compared from 1997 to 2000. The test panel consisted of 14 antibiotics: 3 carbapenems, 3 beta-lactam-beta-lactamase inhibitors, 3 cephamycins, 2 fluoroquinolones, clindamycin, chloramphenicol, and metronidazole. Declines in the geometric mean minimum inhibitory concentrations were seen with imipenem, meropenem, ampicillin-sulbactam, and the cephamycins. Increased geometric means were observed with the fluoroquinolones and were usually accompanied by an increase in resistance rates. Bacteroides distasonis shows the highest resistance rates among beta-lactam antibiotics, whereas Bacteroides vulgatus shows the highest resistance levels among fluoroquinolones. B. fragilis shows the lowest resistance rates for all antibiotics. All strains were susceptible to chloramphenicol and metronidazole concentrations <8 microgram/mL. The data underscore the need for species identification and continued surveillance to monitor resistance patterns.

Duke Scholars

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

September 1, 2002

Volume

35

Issue

Suppl 1

Start / End Page

S126 / S134

Location

United States

Related Subject Headings

  • Microbiology
  • Microbial Sensitivity Tests
  • Humans
  • Drug Resistance, Bacterial
  • Data Collection
  • Bacteroides fragilis
  • Anti-Bacterial Agents
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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MLA
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Snydman, D. R., Jacobus, N. V., McDermott, L. A., Ruthazer, R., Goldstein, E. J. C., Finegold, S. M., … Gorbach, S. L. (2002). National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000. Clin Infect Dis, 35(Suppl 1), S126–S134. https://doi.org/10.1086/341934
Snydman, D. R., N. V. Jacobus, L. A. McDermott, R. Ruthazer, E. J. C. Goldstein, S. M. Finegold, L. J. Harrell, et al. “National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000.Clin Infect Dis 35, no. Suppl 1 (September 1, 2002): S126–34. https://doi.org/10.1086/341934.
Snydman DR, Jacobus NV, McDermott LA, Ruthazer R, Goldstein EJC, Finegold SM, et al. National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000. Clin Infect Dis. 2002 Sep 1;35(Suppl 1):S126–34.
Snydman, D. R., et al. “National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000.Clin Infect Dis, vol. 35, no. Suppl 1, Sept. 2002, pp. S126–34. Pubmed, doi:10.1086/341934.
Snydman DR, Jacobus NV, McDermott LA, Ruthazer R, Goldstein EJC, Finegold SM, Harrell LJ, Hecht DW, Jenkins SG, Pierson C, Venezia R, Rihs J, Gorbach SL. National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000. Clin Infect Dis. 2002 Sep 1;35(Suppl 1):S126–S134.
Journal cover image

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

September 1, 2002

Volume

35

Issue

Suppl 1

Start / End Page

S126 / S134

Location

United States

Related Subject Headings

  • Microbiology
  • Microbial Sensitivity Tests
  • Humans
  • Drug Resistance, Bacterial
  • Data Collection
  • Bacteroides fragilis
  • Anti-Bacterial Agents
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences