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Organized deposits in the kidney and look-alikes.

Publication ,  Journal Article
Howell, DN; Gu, X; Herrera, GA
Published in: Ultrastruct Pathol
2003

Organized or structured deposits are encountered during electron microscopic examination of kidney tissue in a wide variety of primary renal and multisystemic disorders. They are most commonly seen in the renal glomerulus, though extraglomerular sites are occasionally involved. In some cases, organized deposits herald the presence of a specific disease process. Included in this category are organized substances containing immunoglobulin molecules or parts thereof as well as non-immunoglobulin-containing materials that accumulate in several rare heritable disorders. A second broad category of structured deposits includes substances that accumulate in response to nonspecific tissue injuries. In many instances, such "look-alikes" can be difficult to distinguish from disease-specific structured deposits. Ultrastructural pathology is central to the detection and characterization of organized deposits in the kidney and is the primary focus of this paper. Correlative light microscopic studies are often useful, however, and will be described as well.

Duke Scholars

Published In

Ultrastruct Pathol

ISSN

0191-3123

Publication Date

2003

Volume

27

Issue

5

Start / End Page

295 / 312

Location

England

Related Subject Headings

  • Pathology
  • Pathology
  • Microscopy, Electron
  • Kidney Glomerulus
  • Intermediate Filaments
  • Humans
  • Cryoglobulins
  • Antigen-Antibody Complex
  • Amyloid
  • 3202 Clinical sciences
 

Citation

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MLA
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Howell, D. N., Gu, X., & Herrera, G. A. (2003). Organized deposits in the kidney and look-alikes. Ultrastruct Pathol, 27(5), 295–312.
Howell, David N., Xin Gu, and Guillermo A. Herrera. “Organized deposits in the kidney and look-alikes.Ultrastruct Pathol 27, no. 5 (2003): 295–312.
Howell DN, Gu X, Herrera GA. Organized deposits in the kidney and look-alikes. Ultrastruct Pathol. 2003;27(5):295–312.
Howell, David N., et al. “Organized deposits in the kidney and look-alikes.Ultrastruct Pathol, vol. 27, no. 5, 2003, pp. 295–312.
Howell DN, Gu X, Herrera GA. Organized deposits in the kidney and look-alikes. Ultrastruct Pathol. 2003;27(5):295–312.
Journal cover image

Published In

Ultrastruct Pathol

ISSN

0191-3123

Publication Date

2003

Volume

27

Issue

5

Start / End Page

295 / 312

Location

England

Related Subject Headings

  • Pathology
  • Pathology
  • Microscopy, Electron
  • Kidney Glomerulus
  • Intermediate Filaments
  • Humans
  • Cryoglobulins
  • Antigen-Antibody Complex
  • Amyloid
  • 3202 Clinical sciences