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Desmoplastic small round cell tumor: using FISH as an ancillary technique to support cytologic diagnosis in an unusual case.

Publication ,  Journal Article
Waugh, MS; Dash, RC; Turner, KC; Dodd, LG
Published in: Diagn Cytopathol
August 2007

Desmoplastic small round cell tumor is a rare and aggressive neoplasm that predominantly affects young males. In almost all cases, a reciprocal translocation is present resulting in the fusion of the Ewing sarcoma gene with the Wilms' tumor gene. Here we describe an unusual case occurring in a 59-year-old male, in which fluorescence in situ hybridization (FISH) was used in conjunction with immunohistochemical studies to confirm the diagnosis. To our knowledge, this is the first reported case of using FISH as an ancillary technique to confirm the cytologic diagnosis of this tumor.

Duke Scholars

Published In

Diagn Cytopathol

DOI

ISSN

8755-1039

Publication Date

August 2007

Volume

35

Issue

8

Start / End Page

516 / 520

Location

United States

Related Subject Headings

  • RNA-Binding Proteins
  • RNA-Binding Protein EWS
  • Pathology
  • Middle Aged
  • Male
  • Liver Neoplasms
  • In Situ Hybridization, Fluorescence
  • Immunohistochemistry
  • Humans
  • Carcinoma, Small Cell
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Waugh, M. S., Dash, R. C., Turner, K. C., & Dodd, L. G. (2007). Desmoplastic small round cell tumor: using FISH as an ancillary technique to support cytologic diagnosis in an unusual case. Diagn Cytopathol, 35(8), 516–520. https://doi.org/10.1002/dc.20669
Waugh, Michael S., Rajesh C. Dash, Kristi C. Turner, and Leslie G. Dodd. “Desmoplastic small round cell tumor: using FISH as an ancillary technique to support cytologic diagnosis in an unusual case.Diagn Cytopathol 35, no. 8 (August 2007): 516–20. https://doi.org/10.1002/dc.20669.
Waugh, Michael S., et al. “Desmoplastic small round cell tumor: using FISH as an ancillary technique to support cytologic diagnosis in an unusual case.Diagn Cytopathol, vol. 35, no. 8, Aug. 2007, pp. 516–20. Pubmed, doi:10.1002/dc.20669.
Waugh MS, Dash RC, Turner KC, Dodd LG. Desmoplastic small round cell tumor: using FISH as an ancillary technique to support cytologic diagnosis in an unusual case. Diagn Cytopathol. 2007 Aug;35(8):516–520.
Journal cover image

Published In

Diagn Cytopathol

DOI

ISSN

8755-1039

Publication Date

August 2007

Volume

35

Issue

8

Start / End Page

516 / 520

Location

United States

Related Subject Headings

  • RNA-Binding Proteins
  • RNA-Binding Protein EWS
  • Pathology
  • Middle Aged
  • Male
  • Liver Neoplasms
  • In Situ Hybridization, Fluorescence
  • Immunohistochemistry
  • Humans
  • Carcinoma, Small Cell