Skip to main content

Controlling emesis: evolving challenges, novel strategies.

Publication ,  Journal Article
Nevidjon, B; Chaudhary, R
Published in: The journal of supportive oncology
July 2010

Control of nausea and vomiting following chemotherapy, radiation therapy, and surgery has significantly improved in recent years due to the development of novel, effective, and better-tolerated antiemetic therapies. However, the incidence and severity of emesis are often underestimated by the medical community and remain among the most distressing outcomes following treatment. Inadequately controlled nausea and vomiting can negatively impact several aspects of emetogenic therapy, including quality of life, cost of therapy, compliance, and possibly treatment outcomes. To address these concerns, antiemetic therapy continues to evolve along several avenues, such as the development and use of novel 5-hydroxytryptamine and neurokinin-1 receptor antagonists, refinement of antiemetic therapeutic guidelines, identification of additional risk factors for acute and delayed nausea and vomiting, and additional research toward the role of nonpharmacologic complementary therapies. In addition to improved treatment options, the development of alternative oral drug delivery systems, including orally dissolving tablets and film strips, should further improve the overall convenience of antiemetic therapy.

Duke Scholars

Published In

The journal of supportive oncology

EISSN

1879-596X

ISSN

1544-6794

Publication Date

July 2010

Volume

8

Issue

4 Suppl 2

Start / End Page

1 / 10

Related Subject Headings

  • Vomiting
  • Oncology & Carcinogenesis
  • Humans
  • Antiemetics
  • 1117 Public Health and Health Services
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nevidjon, B., & Chaudhary, R. (2010). Controlling emesis: evolving challenges, novel strategies. The Journal of Supportive Oncology, 8(4 Suppl 2), 1–10.
Nevidjon, Brenda, and Rekha Chaudhary. “Controlling emesis: evolving challenges, novel strategies.The Journal of Supportive Oncology 8, no. 4 Suppl 2 (July 2010): 1–10.
Nevidjon B, Chaudhary R. Controlling emesis: evolving challenges, novel strategies. The journal of supportive oncology. 2010 Jul;8(4 Suppl 2):1–10.
Nevidjon, Brenda, and Rekha Chaudhary. “Controlling emesis: evolving challenges, novel strategies.The Journal of Supportive Oncology, vol. 8, no. 4 Suppl 2, July 2010, pp. 1–10.
Nevidjon B, Chaudhary R. Controlling emesis: evolving challenges, novel strategies. The journal of supportive oncology. 2010 Jul;8(4 Suppl 2):1–10.

Published In

The journal of supportive oncology

EISSN

1879-596X

ISSN

1544-6794

Publication Date

July 2010

Volume

8

Issue

4 Suppl 2

Start / End Page

1 / 10

Related Subject Headings

  • Vomiting
  • Oncology & Carcinogenesis
  • Humans
  • Antiemetics
  • 1117 Public Health and Health Services
  • 1112 Oncology and Carcinogenesis