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A fast dose calculation method based on table lookup for IMRT optimization.

Publication ,  Journal Article
Wu, Q; Djajaputra, D; Lauterbach, M; Wu, Y; Mohan, R
Published in: Phys Med Biol
June 21, 2003

This note describes a fast dose calculation method that can be used to speed up the optimization process in intensity-modulated radiotherapy (IMRT). Most iterative optimization algorithms in IMRT require a large number of dose calculations to achieve convergence and therefore the total amount of time needed for the IMRT planning can be substantially reduced by using a faster dose calculation method. The method that is described in this note relies on an accurate dose calculation engine that is used to calculate an approximate dose kernel for each beam used in the treatment plan. Once the kernel is computed and saved, subsequent dose calculations can be done rapidly by looking up this kernel. Inaccuracies due to the approximate nature of the kernel in this method can be reduced by performing scheduled kernel updates. This fast dose calculation method can be performed more than two orders of magnitude faster than the typical superposition/convolution methods and therefore is suitable for applications in which speed is critical, e.g., in an IMRT optimization that requires a simulated annealing optimization algorithm or in a practical IMRT beam-angle optimization system.

Duke Scholars

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

June 21, 2003

Volume

48

Issue

12

Start / End Page

N159 / N166

Location

England

Related Subject Headings

  • Software Design
  • Radiotherapy Planning, Computer-Assisted
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Humans
  • Biophysics
  • Biophysical Phenomena
  • Algorithms
  • 5105 Medical and biological physics
  • 1103 Clinical Sciences
 

Citation

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Wu, Q., Djajaputra, D., Lauterbach, M., Wu, Y., & Mohan, R. (2003). A fast dose calculation method based on table lookup for IMRT optimization. Phys Med Biol, 48(12), N159–N166. https://doi.org/10.1088/0031-9155/48/12/401
Wu, Qiuwen, David Djajaputra, Marc Lauterbach, Yan Wu, and Radhe Mohan. “A fast dose calculation method based on table lookup for IMRT optimization.Phys Med Biol 48, no. 12 (June 21, 2003): N159–66. https://doi.org/10.1088/0031-9155/48/12/401.
Wu Q, Djajaputra D, Lauterbach M, Wu Y, Mohan R. A fast dose calculation method based on table lookup for IMRT optimization. Phys Med Biol. 2003 Jun 21;48(12):N159–66.
Wu, Qiuwen, et al. “A fast dose calculation method based on table lookup for IMRT optimization.Phys Med Biol, vol. 48, no. 12, June 2003, pp. N159–66. Pubmed, doi:10.1088/0031-9155/48/12/401.
Wu Q, Djajaputra D, Lauterbach M, Wu Y, Mohan R. A fast dose calculation method based on table lookup for IMRT optimization. Phys Med Biol. 2003 Jun 21;48(12):N159–N166.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

June 21, 2003

Volume

48

Issue

12

Start / End Page

N159 / N166

Location

England

Related Subject Headings

  • Software Design
  • Radiotherapy Planning, Computer-Assisted
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Humans
  • Biophysics
  • Biophysical Phenomena
  • Algorithms
  • 5105 Medical and biological physics
  • 1103 Clinical Sciences