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An Investigation into the Robustness of Optical-CT Dosimetry of a Radiochromic Dosimeter Compatible with the RPC Head-and-Neck Phantom.

Publication ,  Journal Article
Sakhalkar, HS; Adamovics, J; Ibbott, G; Oldham, M
Published in: J Phys Conf Ser
January 1, 2009

The potential of the PRESAGE™/Optical-CT system as a comprehensive 3D dosimetry tool has been demonstrated. The current study focused on detailed characterization of robustness (intra-dosimeter uniformity and temporal stability) and reproducibility (inter-dosimeter reproducibility) of PRESAGE™ inserts compatible with the RPC H&N phantom. In addition, the accuracy and precision of PRESAGE dose measurement was also evaluated. Four identical PRESAGE™ dosimeters (10cm diameter and 7cm height cylinders) were irradiated with the same rotationally symmetric treatment plan using a Varian accelerator. The treatment plan was designed to rigorously evaluate robustness and reproducibility for multiple dose levels and in 3D. All dosimeters were scanned by optical-CT at daily intervals to study temporal stability. Dose comparisons were made between PRESAGE, ECLIPSE, and independent measurement with EBT film at a select depth. The use of improved optics and acquisition technique yielded substantially higher quality 3D dosimetry data from PRESAGE than has been achieved previously (noise reduced to ~1%, accuracy to within 3%). Data analysis showed excellent intra-dosimeter uniformity, temporal stability and inter-dosimeter reproducibility of relative radiochromic response. In general, the PRESAGE™ dose-distribution was found to agree better with EBT (~99% pass rate) than with ECLIPSE calculations (~92% pass rate) especially in penumbral regions for a 3% dose-difference and 3 mm distance-to-agreement evaluation criteria. The results demonstrate excellent robustness and reproducibility of the PRESAGE™ for relative 3D-dosimetry and represent a significant step towards incorporation in the RadOnc-clinic (e.g. integration with RPC phantom).

Duke Scholars

Published In

J Phys Conf Ser

DOI

ISSN

1742-6588

Publication Date

January 1, 2009

Volume

164

Issue

1

Start / End Page

12059

Location

England

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

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Sakhalkar, H. S., Adamovics, J., Ibbott, G., & Oldham, M. (2009). An Investigation into the Robustness of Optical-CT Dosimetry of a Radiochromic Dosimeter Compatible with the RPC Head-and-Neck Phantom. J Phys Conf Ser, 164(1), 12059. https://doi.org/10.1088/1742-6596/164/1/012059
Sakhalkar, H. S., J. Adamovics, G. Ibbott, and M. Oldham. “An Investigation into the Robustness of Optical-CT Dosimetry of a Radiochromic Dosimeter Compatible with the RPC Head-and-Neck Phantom.J Phys Conf Ser 164, no. 1 (January 1, 2009): 12059. https://doi.org/10.1088/1742-6596/164/1/012059.
Sakhalkar, H. S., et al. “An Investigation into the Robustness of Optical-CT Dosimetry of a Radiochromic Dosimeter Compatible with the RPC Head-and-Neck Phantom.J Phys Conf Ser, vol. 164, no. 1, Jan. 2009, p. 12059. Pubmed, doi:10.1088/1742-6596/164/1/012059.
Journal cover image

Published In

J Phys Conf Ser

DOI

ISSN

1742-6588

Publication Date

January 1, 2009

Volume

164

Issue

1

Start / End Page

12059

Location

England

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics