Malignancy after solid organ transplantation: an overview.
With improving survival following solid organ transplantation, clinicians must be aware of post-transplant complications. One increasingly frequent complication is the development of malignancy after transplantation. The most common malignancies encountered in the post-solid organ transplant setting are nonmelanoma skin cancers, post-transplant lymphoproliferative disorders, and Kaposi's sarcoma (KS). The pathogenesis of these tumors is likely related to the immunosuppressive drugs used post-transplantation and subsequent viral infection. Treatment involves modification of the immunosuppressive drug regimen, resection of localized disease, and chemotherapy. We present the second reported case of a patient with lung transplantation who developed KS in the lung graft.
Duke Scholars
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- Skin Neoplasms
- Sarcoma, Kaposi
- Organ Transplantation
- Oncology & Carcinogenesis
- Neoplasms
- Middle Aged
- Male
- Lymphoproliferative Disorders
- Lung Neoplasms
- Immunocompromised Host
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Skin Neoplasms
- Sarcoma, Kaposi
- Organ Transplantation
- Oncology & Carcinogenesis
- Neoplasms
- Middle Aged
- Male
- Lymphoproliferative Disorders
- Lung Neoplasms
- Immunocompromised Host