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[Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats].

Publication ,  Journal Article
Liberatori Filho, AW; Lopes, RD; Mora, OA; Simões, MJ; Lopes, AC
Published in: Rev Assoc Med Bras (1992)
1999
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PURPOSE: In the present study we evaluated, by light microscopy, and throughout morphometry, whether hypertrophy of cardiac striated muscular fibers of left ventricular occur in albino rat, during pregnancy. METHODS: After maiting, 12 nuliparous rats were divided into four groups with three animals for each group. The female rats corresponding to each group were killed at 1st, 7th, 14th and 21st days of pregnancy. RESULTS: Observation, on light microscopy (H.E) had at one view, did not display any alterations during pregnancy. However, the morphometry revealed that nuclei of cardiomyocytes are augmented in volume at 14th day of pregnancy and statistically significant data show the hypertrophy. CONCLUSION: The obtained data show the existence of a dinamic and reversible process of ventricular remodelling in consequence of adaptation physiological alterations of the cardiovascular normal pregnancy.

Duke Scholars

Renato Delascio Lopes
Author Renato Delascio Lopes Medicine, Cardiology

Published In

Rev Assoc Med Bras (1992)

DOI

10.1590/s0104-42301999000300009

ISSN

0104-4230

Publication Date

1999

Volume

45

Issue

3

Start / End Page

242 / 246

Location

Brazil

Related Subject Headings

  • Rats
  • Pregnancy
  • Hypertrophy, Left Ventricular
  • Heart Ventricles
  • General & Internal Medicine
  • Female
  • Animals
 

Citation

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Liberatori Filho, A. W., Lopes, R. D., Mora, O. A., Simões, M. J., & Lopes, A. C. (1999). [Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats]. Rev Assoc Med Bras (1992), 45(3), 242–246. https://doi.org/10.1590/s0104-42301999000300009
Liberatori Filho, A. W., R. D. Lopes, O. A. Mora, M. J. Simões, and A. C. Lopes. “[Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats].” Rev Assoc Med Bras (1992) 45, no. 3 (1999): 242–46. https://doi.org/10.1590/s0104-42301999000300009.
Liberatori Filho AW, Lopes RD, Mora OA, Simões MJ, Lopes AC. [Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats]. Rev Assoc Med Bras (1992). 1999;45(3):242–6.
Liberatori Filho, A. W., et al. “[Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats].” Rev Assoc Med Bras (1992), vol. 45, no. 3, 1999, pp. 242–46. Pubmed, doi:10.1590/s0104-42301999000300009.
Liberatori Filho AW, Lopes RD, Mora OA, Simões MJ, Lopes AC. [Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats]. Rev Assoc Med Bras (1992). 1999;45(3):242–246.
Journal cover image

Published In

Rev Assoc Med Bras (1992)

DOI

10.1590/s0104-42301999000300009

ISSN

0104-4230

Publication Date

1999

Volume

45

Issue

3

Start / End Page

242 / 246

Location

Brazil

Related Subject Headings

  • Rats
  • Pregnancy
  • Hypertrophy, Left Ventricular
  • Heart Ventricles
  • General & Internal Medicine
  • Female
  • Animals