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Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS.

Publication ,  Journal Article
Relf, MV
Published in: The Journal of the Association of Nurses in AIDS Care : JANAC
September 1996

Despite great advances and a significant understanding of HIV pathogenesis, no curative treatment modality currently exists. Since baboon bone marrow cells (BBMC) are believed to be resistant to the human immunodeficiency virus, researchers have recently transplanted BBMC into two patients with AIDS, a process known as xenotransplantation. The purpose of this paper is to provide a comparative analysis of human and baboon hematopoiesis, followed by a review of the pathophysiologic effects of the HIV on the human hematologic and immune systems. The two protocols implemented since 1994 are discussed, including an overview of the potential risks and benefits and implications for nursing practice.

Duke Scholars

Published In

The Journal of the Association of Nurses in AIDS Care : JANAC

DOI

EISSN

1552-6917

ISSN

1055-3290

Publication Date

September 1996

Volume

7

Issue

5

Start / End Page

27 / 35

Related Subject Headings

  • Transplantation, Heterologous
  • Risk Assessment
  • Public Health
  • Patient Education as Topic
  • Papio
  • Middle Aged
  • Male
  • Leukocytes
  • Humans
  • Hematopoiesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Relf, M. V. (1996). Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS. The Journal of the Association of Nurses in AIDS Care : JANAC, 7(5), 27–35. https://doi.org/10.1016/s1055-3290(96)80043-4
Relf, M. V. “Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS.The Journal of the Association of Nurses in AIDS Care : JANAC 7, no. 5 (September 1996): 27–35. https://doi.org/10.1016/s1055-3290(96)80043-4.
Relf MV. Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS. The Journal of the Association of Nurses in AIDS Care : JANAC. 1996 Sep;7(5):27–35.
Relf, M. V. “Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS.The Journal of the Association of Nurses in AIDS Care : JANAC, vol. 7, no. 5, Sept. 1996, pp. 27–35. Epmc, doi:10.1016/s1055-3290(96)80043-4.
Relf MV. Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS. The Journal of the Association of Nurses in AIDS Care : JANAC. 1996 Sep;7(5):27–35.
Journal cover image

Published In

The Journal of the Association of Nurses in AIDS Care : JANAC

DOI

EISSN

1552-6917

ISSN

1055-3290

Publication Date

September 1996

Volume

7

Issue

5

Start / End Page

27 / 35

Related Subject Headings

  • Transplantation, Heterologous
  • Risk Assessment
  • Public Health
  • Patient Education as Topic
  • Papio
  • Middle Aged
  • Male
  • Leukocytes
  • Humans
  • Hematopoiesis