Mechanisms of anti-DNA production in human and murine SLE.
Publication
, Journal Article
Pisetsky, DS
Published in: In Vivo
1988
Antibodies to DNA occur prominently in systemic lupus erythematosus and play a central role in pathogenesis. Recent studies on the production of anti-DNA antibodies in both mouse and man suggest that this response can result from a variety of immunoregulatory disturbances of B and/or T cells. The immunogenic role of DNA as opposed to other self or foreign antigens remains unclear, however. Future studies will delineate the structure of anti-DNA antibodies and thereby determine the role of antigen drive in this response.
Duke Scholars
Published In
In Vivo
ISSN
0258-851X
Publication Date
1988
Volume
2
Issue
1
Start / End Page
31 / 34
Location
Greece
Related Subject Headings
- Oncology & Carcinogenesis
- Mice
- Lupus Erythematosus, Systemic
- Immunoglobulin Variable Region
- Humans
- DNA
- Autoantibodies
- Antibody Specificity
- Animals
- 3211 Oncology and carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Pisetsky, D. S. (1988). Mechanisms of anti-DNA production in human and murine SLE. In Vivo, 2(1), 31–34.
Pisetsky, D. S. “Mechanisms of anti-DNA production in human and murine SLE.” In Vivo 2, no. 1 (1988): 31–34.
Pisetsky DS. Mechanisms of anti-DNA production in human and murine SLE. In Vivo. 1988;2(1):31–4.
Pisetsky, D. S. “Mechanisms of anti-DNA production in human and murine SLE.” In Vivo, vol. 2, no. 1, 1988, pp. 31–34.
Pisetsky DS. Mechanisms of anti-DNA production in human and murine SLE. In Vivo. 1988;2(1):31–34.
Published In
In Vivo
ISSN
0258-851X
Publication Date
1988
Volume
2
Issue
1
Start / End Page
31 / 34
Location
Greece
Related Subject Headings
- Oncology & Carcinogenesis
- Mice
- Lupus Erythematosus, Systemic
- Immunoglobulin Variable Region
- Humans
- DNA
- Autoantibodies
- Antibody Specificity
- Animals
- 3211 Oncology and carcinogenesis