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Innate immunity and the lung: defense at the interface between host and environment.

Publication ,  Journal Article
Zaas, AK; Schwartz, DA
Published in: Trends Cardiovasc Med
August 2005

The lung serves as a major interface between the host and the external environment. As such, numerous lines of defense protect the host from inhaled potential pathogens. A breach in pulmonary innate immunity can lead to deleterious outcomes, such as pneumonia and disseminated infection. Pulmonary innate immunity, the first line of defense, is mediated by airway and alveolar epithelial cells as well as resident and recruited leukocytes. This article will discuss the key cellular and secreted components of the pulmonary innate immune system.

Duke Scholars

Published In

Trends Cardiovasc Med

DOI

ISSN

1050-1738

Publication Date

August 2005

Volume

15

Issue

6

Start / End Page

195 / 202

Location

United States

Related Subject Headings

  • Lung Diseases
  • Lung
  • Immunity, Innate
  • Immunity, Cellular
  • Humans
  • Environment
  • Defensins
  • Cardiovascular System & Hematology
  • Animals
  • 3201 Cardiovascular medicine and haematology
 

Citation

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MLA
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Zaas, A. K., & Schwartz, D. A. (2005). Innate immunity and the lung: defense at the interface between host and environment. Trends Cardiovasc Med, 15(6), 195–202. https://doi.org/10.1016/j.tcm.2005.07.001
Zaas, Aimee K., and David A. Schwartz. “Innate immunity and the lung: defense at the interface between host and environment.Trends Cardiovasc Med 15, no. 6 (August 2005): 195–202. https://doi.org/10.1016/j.tcm.2005.07.001.
Zaas AK, Schwartz DA. Innate immunity and the lung: defense at the interface between host and environment. Trends Cardiovasc Med. 2005 Aug;15(6):195–202.
Zaas, Aimee K., and David A. Schwartz. “Innate immunity and the lung: defense at the interface between host and environment.Trends Cardiovasc Med, vol. 15, no. 6, Aug. 2005, pp. 195–202. Pubmed, doi:10.1016/j.tcm.2005.07.001.
Zaas AK, Schwartz DA. Innate immunity and the lung: defense at the interface between host and environment. Trends Cardiovasc Med. 2005 Aug;15(6):195–202.
Journal cover image

Published In

Trends Cardiovasc Med

DOI

ISSN

1050-1738

Publication Date

August 2005

Volume

15

Issue

6

Start / End Page

195 / 202

Location

United States

Related Subject Headings

  • Lung Diseases
  • Lung
  • Immunity, Innate
  • Immunity, Cellular
  • Humans
  • Environment
  • Defensins
  • Cardiovascular System & Hematology
  • Animals
  • 3201 Cardiovascular medicine and haematology