Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies.
Publication
, Journal Article
Rao, SV
Published in: Am J Cardiol
September 7, 2009
Antiplatelet therapy is the cornerstone of management in acute coronary syndromes (ACS) and percutaneous coronary intervention. Combination therapy with aspirin and clopidogrel reduces the risk of death, myocardial infarction, or stroke in ACS but increases the risk of major bleeding, which studies indicate is 1%-4% higher when clopidogrel is added to aspirin. Given the association between bleeding and adverse outcomes, minimizing bleeding risk is a clinical priority. This review outlines strategies to reduce both acute and chronic bleeding risk with aspirin and clopidogrel and focuses on dosing of concomitant therapies, vascular access techniques, and mitigating the bleeding risk associated with coronary artery bypass grafting surgery.
Duke Scholars
Published In
Am J Cardiol
DOI
EISSN
1879-1913
Publication Date
September 7, 2009
Volume
104
Issue
5 Suppl
Start / End Page
60C / 63C
Location
United States
Related Subject Headings
- Postoperative Hemorrhage
- Platelet Aggregation Inhibitors
- Myocardial Revascularization
- Humans
- Cardiovascular System & Hematology
- Administration, Oral
- Acute Coronary Syndrome
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Rao, S. V. (2009). Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies. Am J Cardiol, 104(5 Suppl), 60C-63C. https://doi.org/10.1016/j.amjcard.2009.06.024
Rao, Sunil V. “Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies.” Am J Cardiol 104, no. 5 Suppl (September 7, 2009): 60C-63C. https://doi.org/10.1016/j.amjcard.2009.06.024.
Rao SV. Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies. Am J Cardiol. 2009 Sep 7;104(5 Suppl):60C-63C.
Rao, Sunil V. “Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies.” Am J Cardiol, vol. 104, no. 5 Suppl, Sept. 2009, pp. 60C-63C. Pubmed, doi:10.1016/j.amjcard.2009.06.024.
Rao SV. Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies. Am J Cardiol. 2009 Sep 7;104(5 Suppl):60C-63C.
Published In
Am J Cardiol
DOI
EISSN
1879-1913
Publication Date
September 7, 2009
Volume
104
Issue
5 Suppl
Start / End Page
60C / 63C
Location
United States
Related Subject Headings
- Postoperative Hemorrhage
- Platelet Aggregation Inhibitors
- Myocardial Revascularization
- Humans
- Cardiovascular System & Hematology
- Administration, Oral
- Acute Coronary Syndrome
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology