Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions.
Publication
, Journal Article
Twomley, KM; Rao, SV; Becker, RC
Published in: J Thromb Thrombolysis
April 2006
For many years, the traditional treatment for hospitalized patients in the United States who have developed anemia, whether associated with medical illness, surgical procedures or trauma, has been red blood cell transfusion, despite the absence of supporting data in many patient populations. Emerging evidence suggests that transfusions may, in fact, be associated with risk beyond commonly held concerns of microbial transmission and acute antigen-antibody reactions. The following overview represents a biological paradigm for understanding the relationship between medical illness, surgical procedures, inflammatory states, anemia, red blood cell transfusion and immunothrombotic phenomena among hospitalized patients.
Duke Scholars
Published In
J Thromb Thrombolysis
DOI
ISSN
0929-5305
Publication Date
April 2006
Volume
21
Issue
2
Start / End Page
167 / 174
Location
Netherlands
Related Subject Headings
- Thrombosis
- Inflammation
- Humans
- Erythrocyte Transfusion
- Contraindications
- Cardiovascular System & Hematology
- Anemia
- 3202 Clinical sciences
- 3201 Cardiovascular medicine and haematology
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Twomley, K. M., Rao, S. V., & Becker, R. C. (2006). Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions. J Thromb Thrombolysis, 21(2), 167–174. https://doi.org/10.1007/s11239-006-5206-4
Twomley, Katie M., Sunil V. Rao, and Richard C. Becker. “Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions.” J Thromb Thrombolysis 21, no. 2 (April 2006): 167–74. https://doi.org/10.1007/s11239-006-5206-4.
Twomley KM, Rao SV, Becker RC. Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions. J Thromb Thrombolysis. 2006 Apr;21(2):167–74.
Twomley, Katie M., et al. “Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions.” J Thromb Thrombolysis, vol. 21, no. 2, Apr. 2006, pp. 167–74. Pubmed, doi:10.1007/s11239-006-5206-4.
Twomley KM, Rao SV, Becker RC. Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions. J Thromb Thrombolysis. 2006 Apr;21(2):167–174.
Published In
J Thromb Thrombolysis
DOI
ISSN
0929-5305
Publication Date
April 2006
Volume
21
Issue
2
Start / End Page
167 / 174
Location
Netherlands
Related Subject Headings
- Thrombosis
- Inflammation
- Humans
- Erythrocyte Transfusion
- Contraindications
- Cardiovascular System & Hematology
- Anemia
- 3202 Clinical sciences
- 3201 Cardiovascular medicine and haematology
- 1103 Clinical Sciences