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Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases.

Publication ,  Journal Article
Kim, MJJ; Provenzale, JM; Law, M
Published in: Top Magn Reson Imaging
August 2006

The central nervous system undergoes profound and predictable developmental changes during the first few years of life that provide the structural and functional elements necessary for normal neurological development. The establishment and maturation of white matter pathways is a critical component of the developing nervous system. Diffusion tensor imaging (DTI) offers a noninvasive and quantitative means for the evaluation of white matter changes. DTI has contributed to the evaluation of a number of childhood leukoencephalopathies; it has also been used to follow brain maturation in abnormal states, such as premature birth or early brain injury. Furthermore, it has helped characterize the relation between white matter integrity and cognitive abilities. In the future, DTI is expected to play an increasingly large role in defining developmental abnormalities at an early age and in assessing therapies for pediatric disorders such as leukodystrophies.

Duke Scholars

Published In

Top Magn Reson Imaging

DOI

ISSN

0899-3459

Publication Date

August 2006

Volume

17

Issue

4

Start / End Page

265 / 274

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Nerve Fibers, Myelinated
  • Infant, Newborn
  • Infant
  • Humans
  • Diffusion Magnetic Resonance Imaging
  • Demyelinating Diseases
  • Child, Preschool
  • Child
  • Brain Diseases
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kim, M. J. J., Provenzale, J. M., & Law, M. (2006). Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases. Top Magn Reson Imaging, 17(4), 265–274. https://doi.org/10.1097/01.rmr.0000248665.84211.0f
Kim, Michael J. J., James M. Provenzale, and Meng Law. “Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases.Top Magn Reson Imaging 17, no. 4 (August 2006): 265–74. https://doi.org/10.1097/01.rmr.0000248665.84211.0f.
Kim MJJ, Provenzale JM, Law M. Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases. Top Magn Reson Imaging. 2006 Aug;17(4):265–74.
Kim, Michael J. J., et al. “Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases.Top Magn Reson Imaging, vol. 17, no. 4, Aug. 2006, pp. 265–74. Pubmed, doi:10.1097/01.rmr.0000248665.84211.0f.
Kim MJJ, Provenzale JM, Law M. Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases. Top Magn Reson Imaging. 2006 Aug;17(4):265–274.

Published In

Top Magn Reson Imaging

DOI

ISSN

0899-3459

Publication Date

August 2006

Volume

17

Issue

4

Start / End Page

265 / 274

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Nerve Fibers, Myelinated
  • Infant, Newborn
  • Infant
  • Humans
  • Diffusion Magnetic Resonance Imaging
  • Demyelinating Diseases
  • Child, Preschool
  • Child
  • Brain Diseases