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Cerebral perfusion imaging in vasospasm.

Publication ,  Journal Article
Lad, SP; Guzman, R; Kelly, ME; Li, G; Lim, M; Lovbald, K; Steinberg, GK
Published in: Neurosurg Focus
September 15, 2006

Vasospasm following cerebral aneurysm rupture is one of the most devastating sequelae and the most common cause of delayed ischemic neurological deficit (DIND). Because vasospasm also is the most common cause of morbidity and mortality in patients who survive the initial bleeding episode, it is imperative not only to diagnose the condition but also to predict which patients are likely to become symptomatic. The exact pathophysiology of vasospasm is complex and incompletely elucidated. Early recognition of vasospasm is essential because the timely use of several therapeutic interventions can counteract this disease and prevent the occurrence of DIND. However, the prompt implementation of these therapies depends on the ability to predict impending vasospasm or to diagnose it at its early stages. A number of techniques have been developed during the past several decades to evaluate cerebral perfusion, including positron emission tomography, xenon-enhanced computed tomography, single-photon emission computed tomography, perfusion- and diffusion-weighted magnetic resonance imaging, and perfusion computed tomography. In this article, the authors provide a general overview of the currently available perfusion imaging techniques and their applications in treating vasospasm after a patient has suffered a subarachnoid hemorrhage. The use of cerebral perfusion imaging techniques for the early detection of vasospasm is becoming more common and may provide opportunities for early therapeutic intervention to counteract vasospasm in its earliest stages and prevent the occurrence of DINDs.

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Published In

Neurosurg Focus

DOI

EISSN

1092-0684

Publication Date

September 15, 2006

Volume

21

Issue

3

Start / End Page

E7

Location

United States

Related Subject Headings

  • Vasospasm, Intracranial
  • Perfusion
  • Neurology & Neurosurgery
  • Humans
  • Diagnostic Imaging
  • Cerebrovascular Circulation
  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Lad, S. P., Guzman, R., Kelly, M. E., Li, G., Lim, M., Lovbald, K., & Steinberg, G. K. (2006). Cerebral perfusion imaging in vasospasm. Neurosurg Focus, 21(3), E7. https://doi.org/10.3171/foc.2006.21.3.7
Lad, Shivanand P., Raphael Guzman, Michael E. Kelly, Gordon Li, Michael Lim, Karl Lovbald, and Gary K. Steinberg. “Cerebral perfusion imaging in vasospasm.Neurosurg Focus 21, no. 3 (September 15, 2006): E7. https://doi.org/10.3171/foc.2006.21.3.7.
Lad SP, Guzman R, Kelly ME, Li G, Lim M, Lovbald K, et al. Cerebral perfusion imaging in vasospasm. Neurosurg Focus. 2006 Sep 15;21(3):E7.
Lad, Shivanand P., et al. “Cerebral perfusion imaging in vasospasm.Neurosurg Focus, vol. 21, no. 3, Sept. 2006, p. E7. Pubmed, doi:10.3171/foc.2006.21.3.7.
Lad SP, Guzman R, Kelly ME, Li G, Lim M, Lovbald K, Steinberg GK. Cerebral perfusion imaging in vasospasm. Neurosurg Focus. 2006 Sep 15;21(3):E7.

Published In

Neurosurg Focus

DOI

EISSN

1092-0684

Publication Date

September 15, 2006

Volume

21

Issue

3

Start / End Page

E7

Location

United States

Related Subject Headings

  • Vasospasm, Intracranial
  • Perfusion
  • Neurology & Neurosurgery
  • Humans
  • Diagnostic Imaging
  • Cerebrovascular Circulation
  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences