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Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials.

Publication ,  Journal Article
Baker-Smith, CM; Benjamin, DK; Califf, RM; Murphy, MD; Li, JS; Smith, PB
Published in: Clin Pharmacol Ther
June 2010

The incidence of cough in children receiving antihypertension therapy with angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs) is unknown. We analyzed patient-level data from eight randomized trials for the treatment of pediatric hypertension, six of them involving ACEis and two involving ARBs. The incidence of cough in children receiving ACEis (reported cough, 3.2%) was similar to that in children receiving ARBs (reported cough, 1.8%) (P = 0.34). Reports of cough were lower in children than in adults.

Duke Scholars

Published In

Clin Pharmacol Ther

DOI

EISSN

1532-6535

Publication Date

June 2010

Volume

87

Issue

6

Start / End Page

668 / 671

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Prevalence
  • Pharmacology & Pharmacy
  • Male
  • Incidence
  • Hypertension
  • Humans
  • Female
  • Cough
  • Child
 

Citation

APA
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ICMJE
MLA
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Baker-Smith, C. M., Benjamin, D. K., Califf, R. M., Murphy, M. D., Li, J. S., & Smith, P. B. (2010). Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials. Clin Pharmacol Ther, 87(6), 668–671. https://doi.org/10.1038/clpt.2009.231
Baker-Smith, C. M., D. K. Benjamin, R. M. Califf, M. D. Murphy, J. S. Li, and P. B. Smith. “Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials.Clin Pharmacol Ther 87, no. 6 (June 2010): 668–71. https://doi.org/10.1038/clpt.2009.231.
Baker-Smith CM, Benjamin DK, Califf RM, Murphy MD, Li JS, Smith PB. Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials. Clin Pharmacol Ther. 2010 Jun;87(6):668–71.
Baker-Smith, C. M., et al. “Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials.Clin Pharmacol Ther, vol. 87, no. 6, June 2010, pp. 668–71. Pubmed, doi:10.1038/clpt.2009.231.
Baker-Smith CM, Benjamin DK, Califf RM, Murphy MD, Li JS, Smith PB. Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials. Clin Pharmacol Ther. 2010 Jun;87(6):668–671.
Journal cover image

Published In

Clin Pharmacol Ther

DOI

EISSN

1532-6535

Publication Date

June 2010

Volume

87

Issue

6

Start / End Page

668 / 671

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Prevalence
  • Pharmacology & Pharmacy
  • Male
  • Incidence
  • Hypertension
  • Humans
  • Female
  • Cough
  • Child