Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.
Publication
, Journal Article
Haynes, BF; Shimizu, K; Eisenbarth, GS
Published in: J Clin Invest
January 1983
Using a monoclonal antibody (A2B5), which binds to GQ ganglioside, and tetanus toxin, which binds to GD and GT gangliosides, distinct regions of human and rodent thymic epithelial cells have been identified. The lymphoid elements of the thymus do not bind A2B5 or tetanus toxin. The A2B5 and tetanus toxin-binding cells form a network of thymic epithelial cells throughout the thymic subcapsular cortex and thymic medulla and contain thymopoietin and thymosin alpha-1.
Duke Scholars
Published In
J Clin Invest
DOI
ISSN
0021-9738
Publication Date
January 1983
Volume
71
Issue
1
Start / End Page
9 / 14
Location
United States
Related Subject Headings
- Thymus Gland
- Thymosin
- Thymopoietins
- Tetanus Toxin
- Rats
- Mice
- Immunology
- Humans
- Gangliosides
- Fluorescent Antibody Technique
Citation
APA
Chicago
ICMJE
MLA
NLM
Haynes, B. F., Shimizu, K., & Eisenbarth, G. S. (1983). Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5. J Clin Invest, 71(1), 9–14. https://doi.org/10.1172/jci110755
Haynes, B. F., K. Shimizu, and G. S. Eisenbarth. “Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.” J Clin Invest 71, no. 1 (January 1983): 9–14. https://doi.org/10.1172/jci110755.
Haynes BF, Shimizu K, Eisenbarth GS. Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5. J Clin Invest. 1983 Jan;71(1):9–14.
Haynes, B. F., et al. “Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.” J Clin Invest, vol. 71, no. 1, Jan. 1983, pp. 9–14. Pubmed, doi:10.1172/jci110755.
Haynes BF, Shimizu K, Eisenbarth GS. Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5. J Clin Invest. 1983 Jan;71(1):9–14.
Published In
J Clin Invest
DOI
ISSN
0021-9738
Publication Date
January 1983
Volume
71
Issue
1
Start / End Page
9 / 14
Location
United States
Related Subject Headings
- Thymus Gland
- Thymosin
- Thymopoietins
- Tetanus Toxin
- Rats
- Mice
- Immunology
- Humans
- Gangliosides
- Fluorescent Antibody Technique