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CD6-ligand interactions: a paradigm for SRCR domain function?

Publication ,  Journal Article
Aruffo, A; Bowen, MA; Patel, DD; Haynes, BF; Starling, GC; Gebe, JA; Bajorath, J
Published in: Immunol Today
October 1997

The scavenger receptor cysteine-rich (SRCR) superfamily, which includes proteins expressed by leukocytes, can be subdivided into groups A and B. Group B contains the lymphocyte cell-surface receptor CD6. This article reviews recent progress in understanding the interaction between CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM). Analysis of the CD6-ALCAM interaction may help to understand how other SRCR domains bind to their ligands.

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Published In

Immunol Today

DOI

ISSN

0167-5699

Publication Date

October 1997

Volume

18

Issue

10

Start / End Page

498 / 504

Location

England

Related Subject Headings

  • Sequence Homology, Amino Acid
  • Scavenger Receptors, Class B
  • Receptors, Scavenger
  • Receptors, Lipoprotein
  • Receptors, Immunologic
  • Receptors, Cell Surface
  • Molecular Sequence Data
  • Models, Molecular
  • Membrane Proteins
  • Ligands
 

Citation

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Aruffo, A., Bowen, M. A., Patel, D. D., Haynes, B. F., Starling, G. C., Gebe, J. A., & Bajorath, J. (1997). CD6-ligand interactions: a paradigm for SRCR domain function? Immunol Today, 18(10), 498–504. https://doi.org/10.1016/s0167-5699(97)01130-4
Aruffo, A., M. A. Bowen, D. D. Patel, B. F. Haynes, G. C. Starling, J. A. Gebe, and J. Bajorath. “CD6-ligand interactions: a paradigm for SRCR domain function?Immunol Today 18, no. 10 (October 1997): 498–504. https://doi.org/10.1016/s0167-5699(97)01130-4.
Aruffo A, Bowen MA, Patel DD, Haynes BF, Starling GC, Gebe JA, et al. CD6-ligand interactions: a paradigm for SRCR domain function? Immunol Today. 1997 Oct;18(10):498–504.
Aruffo, A., et al. “CD6-ligand interactions: a paradigm for SRCR domain function?Immunol Today, vol. 18, no. 10, Oct. 1997, pp. 498–504. Pubmed, doi:10.1016/s0167-5699(97)01130-4.
Aruffo A, Bowen MA, Patel DD, Haynes BF, Starling GC, Gebe JA, Bajorath J. CD6-ligand interactions: a paradigm for SRCR domain function? Immunol Today. 1997 Oct;18(10):498–504.

Published In

Immunol Today

DOI

ISSN

0167-5699

Publication Date

October 1997

Volume

18

Issue

10

Start / End Page

498 / 504

Location

England

Related Subject Headings

  • Sequence Homology, Amino Acid
  • Scavenger Receptors, Class B
  • Receptors, Scavenger
  • Receptors, Lipoprotein
  • Receptors, Immunologic
  • Receptors, Cell Surface
  • Molecular Sequence Data
  • Models, Molecular
  • Membrane Proteins
  • Ligands