Skip to main content

Opioid management and dependency among adult patients with sickle cell disease.

Publication ,  Journal Article
Feliu, MH; Wellington, C; Crawford, RD; Wood, M; Edwards, L; Byrd, G; Edwards, CL
Published in: Hemoglobin
2011

While pain is one of the most debilitating symptoms of sickle cell disease, narcotics remain an effective although controversial widely practiced intervention. Vaso-occlusive crises are the most common cause for seeking pharmacological treatment. The influence of stigmatization and pseudo addiction in emergency departments and outpatient clinics was reviewed. We analyzed patterns of narcotic utilization in a sample of 63 adult patients with sickle cell disease to determine if their psychological functioning and reports of pain differed as a function of the primary narcotics they were taking for oral pain management. Fifty-one percent of patients reported treatment of Oxycodone, 35% OxyContin, 24% methadone and 11% morphine. Patients who were treated with Oxycodone reported greater sensory reactions to pain (p = 0.001), visual analog scale (VAS) (p = 0.02), and averaged weekly pain intensity ratings than patients who did not use this medication. There were no differences in pain or affective response in patients treated with OxyContin, methadone or morphine. We suggest there are clear differences between the reports of pain in patients with sickle cell disease taking short-acting narcotics for pain management as compared to those who are not, a pattern that does not distinguish patients who are managed with long-acting preparations. We discuss the relevance of addressing narcotic management in the context of the perception of health care providers and patients with sickle cell disease.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Hemoglobin

DOI

EISSN

1532-432X

Publication Date

2011

Volume

35

Issue

5-6

Start / End Page

485 / 494

Location

England

Related Subject Headings

  • Young Adult
  • Pain Measurement
  • Pain Management
  • Opioid-Related Disorders
  • Middle Aged
  • Male
  • Immunology
  • Humans
  • Female
  • Anemia, Sickle Cell
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Feliu, M. H., Wellington, C., Crawford, R. D., Wood, M., Edwards, L., Byrd, G., & Edwards, C. L. (2011). Opioid management and dependency among adult patients with sickle cell disease. Hemoglobin, 35(5–6), 485–494. https://doi.org/10.3109/03630269.2011.610914
Feliu, Miriam H., Chante Wellington, Regina D. Crawford, Mary Wood, Lekisha Edwards, Goldie Byrd, and Christopher L. Edwards. “Opioid management and dependency among adult patients with sickle cell disease.Hemoglobin 35, no. 5–6 (2011): 485–94. https://doi.org/10.3109/03630269.2011.610914.
Feliu MH, Wellington C, Crawford RD, Wood M, Edwards L, Byrd G, et al. Opioid management and dependency among adult patients with sickle cell disease. Hemoglobin. 2011;35(5–6):485–94.
Feliu, Miriam H., et al. “Opioid management and dependency among adult patients with sickle cell disease.Hemoglobin, vol. 35, no. 5–6, 2011, pp. 485–94. Pubmed, doi:10.3109/03630269.2011.610914.
Feliu MH, Wellington C, Crawford RD, Wood M, Edwards L, Byrd G, Edwards CL. Opioid management and dependency among adult patients with sickle cell disease. Hemoglobin. 2011;35(5–6):485–494.

Published In

Hemoglobin

DOI

EISSN

1532-432X

Publication Date

2011

Volume

35

Issue

5-6

Start / End Page

485 / 494

Location

England

Related Subject Headings

  • Young Adult
  • Pain Measurement
  • Pain Management
  • Opioid-Related Disorders
  • Middle Aged
  • Male
  • Immunology
  • Humans
  • Female
  • Anemia, Sickle Cell