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Longitudinal evaluation of fine motor skills in children with leukemia.

Publication ,  Journal Article
Hockenberry, M; Krull, K; Moore, K; Gregurich, MA; Casey, ME; Kaemingk, K
Published in: Journal of pediatric hematology/oncology
August 2007

Improved survival for children with acute lymphocytic leukemia (ALL) has allowed investigators to focus on the adverse or side effects of treatment and to develop interventions that promote cure while decreasing the long-term effects of therapy. Although much attention has been given to the significant neurocognitive sequelae that can occur after ALL therapy, limited investigation is found addressing fine motor function in these children and motor function that may contribute to neurocognitive deficits in ALL survivors.Fine motor and sensory-perceptual performances were examined in 82 children with ALL within 6-months of diagnosis and annually for 2 years (year 1 and year 2, respectively) during therapy.Purdue Pegboard assessments indicated significant slowing of fine motor speed and dexterity for the dominant hand, nondominant hand, and both hands simultaneously for children in this study. Mean Visual-Motor Integration (VMI) scores for children with low-risk and high-risk ALL decreased from the first evaluation to year 1 and again at year 2. Mean VMI scores for children with standard risk ALL increased from the first evaluation to year 1 and then decreased at year 2. Significant positive correlations were found between the Purdue and the VMI at both year 1 and year 2, suggesting that the Pegboard performance consistently predicts the later decline in visual-motor integration. Significant correlations were found between the Purdue Pegboard at baseline and the Performance IQ during year 1, though less consistently during year 2. A similar pattern was also observed between the baseline Pegboard performance and performance on the Coding and Symbol Search subtests during year 1 and year 2.In this study, children with ALL experienced significant and persistent visual-motor problems throughout therapy. These problems continued during the first and second years of treatment. These basic processing skills are necessary to the development of higher-level cognitive abilities, including nonverbal intelligence and academic achievement, particularly in arithmetic and written language.

Duke Scholars

Published In

Journal of pediatric hematology/oncology

DOI

EISSN

1536-3678

ISSN

1077-4114

Publication Date

August 2007

Volume

29

Issue

8

Start / End Page

535 / 539

Related Subject Headings

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Perception
  • Oncology & Carcinogenesis
  • Motor Skills
  • Male
  • Longitudinal Studies
  • Humans
  • Female
  • Child, Preschool
  • Child
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hockenberry, M., Krull, K., Moore, K., Gregurich, M. A., Casey, M. E., & Kaemingk, K. (2007). Longitudinal evaluation of fine motor skills in children with leukemia. Journal of Pediatric Hematology/Oncology, 29(8), 535–539. https://doi.org/10.1097/mph.0b013e3180f61b92
Hockenberry, Marilyn, Kevin Krull, Ki Moore, Mary Ann Gregurich, Marissa E. Casey, and Kris Kaemingk. “Longitudinal evaluation of fine motor skills in children with leukemia.Journal of Pediatric Hematology/Oncology 29, no. 8 (August 2007): 535–39. https://doi.org/10.1097/mph.0b013e3180f61b92.
Hockenberry M, Krull K, Moore K, Gregurich MA, Casey ME, Kaemingk K. Longitudinal evaluation of fine motor skills in children with leukemia. Journal of pediatric hematology/oncology. 2007 Aug;29(8):535–9.
Hockenberry, Marilyn, et al. “Longitudinal evaluation of fine motor skills in children with leukemia.Journal of Pediatric Hematology/Oncology, vol. 29, no. 8, Aug. 2007, pp. 535–39. Epmc, doi:10.1097/mph.0b013e3180f61b92.
Hockenberry M, Krull K, Moore K, Gregurich MA, Casey ME, Kaemingk K. Longitudinal evaluation of fine motor skills in children with leukemia. Journal of pediatric hematology/oncology. 2007 Aug;29(8):535–539.

Published In

Journal of pediatric hematology/oncology

DOI

EISSN

1536-3678

ISSN

1077-4114

Publication Date

August 2007

Volume

29

Issue

8

Start / End Page

535 / 539

Related Subject Headings

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Perception
  • Oncology & Carcinogenesis
  • Motor Skills
  • Male
  • Longitudinal Studies
  • Humans
  • Female
  • Child, Preschool
  • Child