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Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia.

Publication ,  Journal Article
Rao, AV; Valk, PJM; Metzeler, KH; Acharya, CR; Tuchman, SA; Stevenson, MM; Rizzieri, DA; Delwel, R; Buske, C; Bohlander, SK; Potti, A; Löwenberg, B
Published in: J Clin Oncol
November 20, 2009

PURPOSE: To define the biology driving the aggressive nature of acute myeloid leukemia (AML) in elderly patients. PATIENTS AND METHODS: Clinically annotated microarray data from 425 patients with newly diagnosed de novo AML from two publicly available data sets were analyzed after age-specific cohorts (young

Duke Scholars

Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

November 20, 2009

Volume

27

Issue

33

Start / End Page

5580 / 5586

Location

United States

Related Subject Headings

  • fms-Like Tyrosine Kinase 3
  • Young Adult
  • Treatment Outcome
  • Survival Analysis
  • Statistics, Nonparametric
  • Severity of Illness Index
  • Risk Assessment
  • Prospective Studies
  • Prognosis
  • Probability
 

Citation

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Rao, A. V., Valk, P. J. M., Metzeler, K. H., Acharya, C. R., Tuchman, S. A., Stevenson, M. M., … Löwenberg, B. (2009). Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia. J Clin Oncol, 27(33), 5580–5586. https://doi.org/10.1200/JCO.2009.22.2547
Rao, Arati V., Peter J. M. Valk, Klaus H. Metzeler, Chaitanya R. Acharya, Sascha A. Tuchman, Marvaretta M. Stevenson, David A. Rizzieri, et al. “Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia.J Clin Oncol 27, no. 33 (November 20, 2009): 5580–86. https://doi.org/10.1200/JCO.2009.22.2547.
Rao AV, Valk PJM, Metzeler KH, Acharya CR, Tuchman SA, Stevenson MM, et al. Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia. J Clin Oncol. 2009 Nov 20;27(33):5580–6.
Rao, Arati V., et al. “Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia.J Clin Oncol, vol. 27, no. 33, Nov. 2009, pp. 5580–86. Pubmed, doi:10.1200/JCO.2009.22.2547.
Rao AV, Valk PJM, Metzeler KH, Acharya CR, Tuchman SA, Stevenson MM, Rizzieri DA, Delwel R, Buske C, Bohlander SK, Potti A, Löwenberg B. Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia. J Clin Oncol. 2009 Nov 20;27(33):5580–5586.

Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

November 20, 2009

Volume

27

Issue

33

Start / End Page

5580 / 5586

Location

United States

Related Subject Headings

  • fms-Like Tyrosine Kinase 3
  • Young Adult
  • Treatment Outcome
  • Survival Analysis
  • Statistics, Nonparametric
  • Severity of Illness Index
  • Risk Assessment
  • Prospective Studies
  • Prognosis
  • Probability