Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method.
Publication
, Journal Article
Ostrosky-Zeichner, L; Rex, JH; Pfaller, MA; Diekema, DJ; Alexander, BD; Andes, D; Brown, SD; Chaturvedi, V; Ghannoum, MA; Knapp, CC; Walsh, TJ ...
Published in: Antimicrob Agents Chemother
November 2008
We investigated if CLSI M27-A2 Candida species breakpoints for fluconazole MIC are valid when read at 24 h. Analysis of a data set showed good correlation between 48- and 24-h MICs, as well as similar outcomes and pharmacodynamic efficacy parameters, except for isolates in the susceptible dose-dependent category, such as Candida glabrata.
Duke Scholars
Published In
Antimicrob Agents Chemother
DOI
EISSN
1098-6596
Publication Date
November 2008
Volume
52
Issue
11
Start / End Page
4175 / 4177
Location
United States
Related Subject Headings
- Time Factors
- Models, Biological
- Microbiology
- Microbial Sensitivity Tests
- Humans
- Fluconazole
- Databases, Factual
- Candidiasis
- Candida
- Antifungal Agents
Citation
APA
Chicago
ICMJE
MLA
NLM
Ostrosky-Zeichner, L., Rex, J. H., Pfaller, M. A., Diekema, D. J., Alexander, B. D., Andes, D., … Walsh, T. J. (2008). Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method. Antimicrob Agents Chemother, 52(11), 4175–4177. https://doi.org/10.1128/AAC.00420-08
Ostrosky-Zeichner, Luis, John H. Rex, Michael A. Pfaller, Daniel J. Diekema, Barbara D. Alexander, David Andes, Steven D. Brown, et al. “Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method.” Antimicrob Agents Chemother 52, no. 11 (November 2008): 4175–77. https://doi.org/10.1128/AAC.00420-08.
Ostrosky-Zeichner L, Rex JH, Pfaller MA, Diekema DJ, Alexander BD, Andes D, et al. Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method. Antimicrob Agents Chemother. 2008 Nov;52(11):4175–7.
Ostrosky-Zeichner, Luis, et al. “Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method.” Antimicrob Agents Chemother, vol. 52, no. 11, Nov. 2008, pp. 4175–77. Pubmed, doi:10.1128/AAC.00420-08.
Ostrosky-Zeichner L, Rex JH, Pfaller MA, Diekema DJ, Alexander BD, Andes D, Brown SD, Chaturvedi V, Ghannoum MA, Knapp CC, Sheehan DJ, Walsh TJ. Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method. Antimicrob Agents Chemother. 2008 Nov;52(11):4175–4177.
Published In
Antimicrob Agents Chemother
DOI
EISSN
1098-6596
Publication Date
November 2008
Volume
52
Issue
11
Start / End Page
4175 / 4177
Location
United States
Related Subject Headings
- Time Factors
- Models, Biological
- Microbiology
- Microbial Sensitivity Tests
- Humans
- Fluconazole
- Databases, Factual
- Candidiasis
- Candida
- Antifungal Agents