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Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin.

Publication ,  Journal Article
Fuller, RE; Drew, RH; Perfect, JR
Published in: Pharmacotherapy
1996

Enterococci are the second most common cause of hospital-acquired infections, and drug resistance among these organisms is a growing problem. Vancomycin-resistant enterococci (VRE) now account for 7.9% of the nosocomial enterococcal infections. There is no standard therapy for VRE. Although some agents have shown in vitro activity alone or in combination, including ciprofloxacin, doxycycline, novobiocin, teicoplanin, chloramphenicol, and rifampin, treatment options are limited to combinations of drugs with marginal efficacy against the pathogens. Quinupristin-dalfopristin is a new investigational agent with activity against gram-positive cocci, including VRE.

Duke Scholars

Published In

Pharmacotherapy

ISSN

0277-0008

Publication Date

1996

Volume

16

Issue

4

Start / End Page

584 / 592

Location

United States

Related Subject Headings

  • Virginiamycin
  • Vancomycin
  • Pharmacology & Pharmacy
  • Humans
  • Enterococcus
  • Drug Therapy, Combination
  • Drug Resistance, Microbial
  • Clinical Trials, Phase III as Topic
  • Anti-Bacterial Agents
  • 3214 Pharmacology and pharmaceutical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Fuller, R. E., Drew, R. H., & Perfect, J. R. (1996). Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin. Pharmacotherapy, 16(4), 584–592.
Fuller, R. E., R. H. Drew, and J. R. Perfect. “Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin.Pharmacotherapy 16, no. 4 (1996): 584–92.
Fuller RE, Drew RH, Perfect JR. Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin. Pharmacotherapy. 1996;16(4):584–92.
Fuller, R. E., et al. “Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin.Pharmacotherapy, vol. 16, no. 4, 1996, pp. 584–92.
Fuller RE, Drew RH, Perfect JR. Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin. Pharmacotherapy. 1996;16(4):584–592.

Published In

Pharmacotherapy

ISSN

0277-0008

Publication Date

1996

Volume

16

Issue

4

Start / End Page

584 / 592

Location

United States

Related Subject Headings

  • Virginiamycin
  • Vancomycin
  • Pharmacology & Pharmacy
  • Humans
  • Enterococcus
  • Drug Therapy, Combination
  • Drug Resistance, Microbial
  • Clinical Trials, Phase III as Topic
  • Anti-Bacterial Agents
  • 3214 Pharmacology and pharmaceutical sciences