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Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat.

Publication ,  Journal Article
Goldstein, LB; Davis, JN
Published in: Restor Neurol Neurosci
January 1, 1990

Treatment with amphetamine increases the rate of recovery of beam-walking in rats when administered after a unilateral suction-ablation lesion of the sensorimotor cortex. It is thought that amphetamine treatment must be combined with postlesion practice on the beam since confinement to prevent locomotion blocks amphetamine-facilitated recovery. However, rats which are confined are also isolated and not handled. In the present experiment, beam-walking recovery was compared among groups of rats which were treated with either amphetamine or saline and then either handled and allowed to walk in a home cage or given practice on the beam. Although amphetamine treatment and postlesion practice had independent beneficial effects on recovery, the group of rats given both treatments had the greatest improvement in beam-walking scores.

Duke Scholars

Published In

Restor Neurol Neurosci

DOI

ISSN

0922-6028

Publication Date

January 1, 1990

Volume

1

Issue

5

Start / End Page

311 / 314

Location

Netherlands

Related Subject Headings

  • Neurology & Neurosurgery
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
 

Citation

APA
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MLA
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Goldstein, L. B., & Davis, J. N. (1990). Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat. Restor Neurol Neurosci, 1(5), 311–314. https://doi.org/10.3233/RNN-1990-1501
Goldstein, L. B., and J. N. Davis. “Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat.Restor Neurol Neurosci 1, no. 5 (January 1, 1990): 311–14. https://doi.org/10.3233/RNN-1990-1501.
Goldstein LB, Davis JN. Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat. Restor Neurol Neurosci. 1990 Jan 1;1(5):311–4.
Goldstein, L. B., and J. N. Davis. “Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat.Restor Neurol Neurosci, vol. 1, no. 5, Jan. 1990, pp. 311–14. Pubmed, doi:10.3233/RNN-1990-1501.
Goldstein LB, Davis JN. Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat. Restor Neurol Neurosci. 1990 Jan 1;1(5):311–314.

Published In

Restor Neurol Neurosci

DOI

ISSN

0922-6028

Publication Date

January 1, 1990

Volume

1

Issue

5

Start / End Page

311 / 314

Location

Netherlands

Related Subject Headings

  • Neurology & Neurosurgery
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences