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Clinical characteristics and long-term survival of patients with variant angina.

Publication ,  Journal Article
Mark, DB; Califf, RM; Morris, KG; Harrell, FE; Pryor, DB; Hlatky, MA; Lee, KL; Rosati, RA
Published in: Circulation
May 1984

We studied 109 consecutive patients with variant angina who underwent cardiac catheterization over an 11 year period. All patients were followed for at least 6 months or until death, and 46 patients (22 treated medically and 24 treated surgically) were followed for 5 years or more. Of the 62 patients initially treated medically, 14 had nonfatal myocardial infarctions (12 within 1 month of catheterization) and 12 died (six within 6 months). Survival probabilities at 1, 3, and 5 years were 0.88, 0.84, and 0.77, respectively. Of the 48 surgically treated patients (including four patients initially treated medically and one initially treated with coronary angioplasty), four had nonfatal infarctions (three in the perioperative period) and three died (all in the perioperative period). The survival probability in these patients at 1 year was 0.94 and remained unchanged at 3 and 5 years. Only one nonfatal infarction and no deaths have occurred in the group of surgically treated patients subsequent to hospital discharge. Three additional patients were treated with coronary angioplasty. The single most important prognostic factor in medically treated patients was the presence or absence of fixed obstructive coronary artery disease. Infarction-free survival probabilities at 1 and 3 years in the 23 patients without significant coronary artery disease were 1.0 and 0.89, compared with 0.51 and 0.46 in the 39 patients with significant coronary disease. Analysis by the Cox model showed that variant angina patients had a higher probability of death and nonfatal infarction than did those with nonvariant angina coronary disease if other important prognostic variables were held constant.(ABSTRACT TRUNCATED AT 250 WORDS)

Duke Scholars

Published In

Circulation

DOI

ISSN

0009-7322

Publication Date

May 1984

Volume

69

Issue

5

Start / End Page

880 / 888

Location

United States

Related Subject Headings

  • Prognosis
  • Middle Aged
  • Male
  • Humans
  • Coronary Disease
  • Cardiovascular System & Hematology
  • Cardiac Catheterization
  • Angina Pectoris, Variant
  • 4207 Sports science and exercise
  • 3202 Clinical sciences
 

Citation

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MLA
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Mark, D. B., Califf, R. M., Morris, K. G., Harrell, F. E., Pryor, D. B., Hlatky, M. A., … Rosati, R. A. (1984). Clinical characteristics and long-term survival of patients with variant angina. Circulation, 69(5), 880–888. https://doi.org/10.1161/01.cir.69.5.880
Mark, D. B., R. M. Califf, K. G. Morris, F. E. Harrell, D. B. Pryor, M. A. Hlatky, K. L. Lee, and R. A. Rosati. “Clinical characteristics and long-term survival of patients with variant angina.Circulation 69, no. 5 (May 1984): 880–88. https://doi.org/10.1161/01.cir.69.5.880.
Mark DB, Califf RM, Morris KG, Harrell FE, Pryor DB, Hlatky MA, et al. Clinical characteristics and long-term survival of patients with variant angina. Circulation. 1984 May;69(5):880–8.
Mark, D. B., et al. “Clinical characteristics and long-term survival of patients with variant angina.Circulation, vol. 69, no. 5, May 1984, pp. 880–88. Pubmed, doi:10.1161/01.cir.69.5.880.
Mark DB, Califf RM, Morris KG, Harrell FE, Pryor DB, Hlatky MA, Lee KL, Rosati RA. Clinical characteristics and long-term survival of patients with variant angina. Circulation. 1984 May;69(5):880–888.

Published In

Circulation

DOI

ISSN

0009-7322

Publication Date

May 1984

Volume

69

Issue

5

Start / End Page

880 / 888

Location

United States

Related Subject Headings

  • Prognosis
  • Middle Aged
  • Male
  • Humans
  • Coronary Disease
  • Cardiovascular System & Hematology
  • Cardiac Catheterization
  • Angina Pectoris, Variant
  • 4207 Sports science and exercise
  • 3202 Clinical sciences