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Infrequent, task-irrelevant monetary gains and losses engage dorsolateral and ventrolateral prefrontal cortex.

Publication ,  Journal Article
Mullette-Gillman, OA; Detwiler, JM; Winecoff, A; Dobbins, I; Huettel, SA
Published in: Brain research
June 2011

Decision making is commonly conceived to reflect the interplay of mutually antagonistic systems: executive processes must inhibit affective information to make adaptive choices. Consistent with this interpretation, prior studies have shown that the dorsolateral prefrontal cortex (dlPFC) is activated by executive processing and deactivated during emotional processing, with the reverse pattern found within the ventrolateral prefrontal cortex (vlPFC). To evaluate whether this pattern generalizes to other affective stimuli--here, monetary rewards--we modified the emotional oddball task to use behaviorally irrelevant reward stimuli, while matching analysis methods and task parameters to those of previous research. Contrary to the double-dissociation model advanced for emotional stimuli, we found that monetary stimuli produced activations within both the dlPFC and the vlPFC. This suggests that monetary stimuli are treated like affective stimuli by vlPFC but like task-relevant target stimuli by dlPFC. Our results suggest differential functional roles in affective and executive processing for these brain regions: the dlPFC supports contingency processing, while the vlPFC evaluates affective or conceptual information.

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Published In

Brain research

DOI

EISSN

1872-6240

ISSN

0006-8993

Publication Date

June 2011

Volume

1395

Start / End Page

53 / 61

Related Subject Headings

  • Young Adult
  • Reward
  • Prefrontal Cortex
  • Neurology & Neurosurgery
  • Male
  • Learning
  • Humans
  • Female
  • Executive Function
  • Corpus Striatum
 

Citation

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Mullette-Gillman, O. A., Detwiler, J. M., Winecoff, A., Dobbins, I., & Huettel, S. A. (2011). Infrequent, task-irrelevant monetary gains and losses engage dorsolateral and ventrolateral prefrontal cortex. Brain Research, 1395, 53–61. https://doi.org/10.1016/j.brainres.2011.04.026
Mullette-Gillman, O’Dhaniel A., Jacqueline M. Detwiler, Amy Winecoff, Ian Dobbins, and Scott A. Huettel. “Infrequent, task-irrelevant monetary gains and losses engage dorsolateral and ventrolateral prefrontal cortex.Brain Research 1395 (June 2011): 53–61. https://doi.org/10.1016/j.brainres.2011.04.026.
Mullette-Gillman OA, Detwiler JM, Winecoff A, Dobbins I, Huettel SA. Infrequent, task-irrelevant monetary gains and losses engage dorsolateral and ventrolateral prefrontal cortex. Brain research. 2011 Jun;1395:53–61.
Mullette-Gillman, O’Dhaniel A., et al. “Infrequent, task-irrelevant monetary gains and losses engage dorsolateral and ventrolateral prefrontal cortex.Brain Research, vol. 1395, June 2011, pp. 53–61. Epmc, doi:10.1016/j.brainres.2011.04.026.
Mullette-Gillman OA, Detwiler JM, Winecoff A, Dobbins I, Huettel SA. Infrequent, task-irrelevant monetary gains and losses engage dorsolateral and ventrolateral prefrontal cortex. Brain research. 2011 Jun;1395:53–61.
Journal cover image

Published In

Brain research

DOI

EISSN

1872-6240

ISSN

0006-8993

Publication Date

June 2011

Volume

1395

Start / End Page

53 / 61

Related Subject Headings

  • Young Adult
  • Reward
  • Prefrontal Cortex
  • Neurology & Neurosurgery
  • Male
  • Learning
  • Humans
  • Female
  • Executive Function
  • Corpus Striatum