Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine.
Publication
, Journal Article
Ying, Y; Kim, H; Hong, J
Published in: Organic letters
February 2011
Both 2,6-cis- and 2,6-trans-piperidines were prepared from common substrates through organocatalytic aza-Michael reactions promoted by the gem-disubstituent effect in conjunction with dithiane coupling reactions. The organocatalytic aza-Michael reaction enabled a facile synthesis of (+)-myrtine and (-)-epimyrtine from a common substrate.
Duke Scholars
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
February 2011
Volume
13
Issue
4
Start / End Page
796 / 799
Related Subject Headings
- Sulfur Compounds
- Stereoisomerism
- Quinolizines
- Quinazolines
- Piperidines
- Organic Chemistry
- Molecular Structure
- Catalysis
- 34 Chemical sciences
- 03 Chemical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Ying, Y., Kim, H., & Hong, J. (2011). Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine. Organic Letters, 13(4), 796–799. https://doi.org/10.1021/ol103064f
Ying, Yongcheng, Hyoungsu Kim, and Jiyong Hong. “Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine.” Organic Letters 13, no. 4 (February 2011): 796–99. https://doi.org/10.1021/ol103064f.
Ying Y, Kim H, Hong J. Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine. Organic letters. 2011 Feb;13(4):796–9.
Ying, Yongcheng, et al. “Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine.” Organic Letters, vol. 13, no. 4, Feb. 2011, pp. 796–99. Epmc, doi:10.1021/ol103064f.
Ying Y, Kim H, Hong J. Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine. Organic letters. 2011 Feb;13(4):796–799.
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
February 2011
Volume
13
Issue
4
Start / End Page
796 / 799
Related Subject Headings
- Sulfur Compounds
- Stereoisomerism
- Quinolizines
- Quinazolines
- Piperidines
- Organic Chemistry
- Molecular Structure
- Catalysis
- 34 Chemical sciences
- 03 Chemical Sciences