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Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: comparison of blood volume and bolus peak arrival time.

Publication ,  Journal Article
Soher, BJ; Gillard, JH; Bryan, RN; Oppenheimer, SM; Barker, PB
Published in: J Stroke Cerebrovasc Dis
1998

Ten patients with a diagnosis of acute middle cerebral artery stroke were evaluated using perfusion magnetic resonance imaging (MRI) during bolus injection of gadolinium diethylenetriaminepentaacetic acid (GdDTPA), MR angiography, and conventional MRI. Scans were performed within 24 hours of symptoms, onset, and 5 of the 10 patients had follow-up MR scans 3 or more days later to determine radiological outcome. Perfusion data were analyzed in terms of relative regional cerebral blood volume (rCBV) and bolus peak arrival times (BAT). Although relative rCBV values overall showed no significant changes compared with contralateral regions of interest, BAT was significantly increased in both infarct and peri-infarct regions. Areas of abnormal BAT significantly exceeded areas of T(2) hyperintensity in acute studies; follow-up images indicated that the size of infarction increased to include some regions with previously abnormal BAT. BAT appears to be a more sensitive parameter for the detection of abnormal cerebral perfusion than rCBV. Used in conjunction with other MR methods, perfusion MR imaging may allow visualization of ischemic tissue at risk of infarction in acute stroke.

Duke Scholars

Published In

J Stroke Cerebrovasc Dis

DOI

ISSN

1052-3057

Publication Date

1998

Volume

7

Issue

1

Start / End Page

17 / 23

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
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ICMJE
MLA
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Soher, B. J., Gillard, J. H., Bryan, R. N., Oppenheimer, S. M., & Barker, P. B. (1998). Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: comparison of blood volume and bolus peak arrival time. J Stroke Cerebrovasc Dis, 7(1), 17–23. https://doi.org/10.1016/s1052-3057(98)80017-7
Soher, B. J., J. H. Gillard, R. N. Bryan, S. M. Oppenheimer, and P. B. Barker. “Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: comparison of blood volume and bolus peak arrival time.J Stroke Cerebrovasc Dis 7, no. 1 (1998): 17–23. https://doi.org/10.1016/s1052-3057(98)80017-7.
Soher BJ, Gillard JH, Bryan RN, Oppenheimer SM, Barker PB. Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: comparison of blood volume and bolus peak arrival time. J Stroke Cerebrovasc Dis. 1998;7(1):17–23.
Soher, B. J., et al. “Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: comparison of blood volume and bolus peak arrival time.J Stroke Cerebrovasc Dis, vol. 7, no. 1, 1998, pp. 17–23. Pubmed, doi:10.1016/s1052-3057(98)80017-7.
Soher BJ, Gillard JH, Bryan RN, Oppenheimer SM, Barker PB. Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: comparison of blood volume and bolus peak arrival time. J Stroke Cerebrovasc Dis. 1998;7(1):17–23.
Journal cover image

Published In

J Stroke Cerebrovasc Dis

DOI

ISSN

1052-3057

Publication Date

1998

Volume

7

Issue

1

Start / End Page

17 / 23

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences