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Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis.

Publication ,  Journal Article
Soher, BJ; Vermathen, P; Schuff, N; Wiedermann, D; Meyerhoff, DJ; Weiner, MW; Maudsley, AA
Published in: Magn Reson Imaging
November 2000

Spectral analysis of short TE in vivo proton magnetic resonance spectroscopic imaging (MRSI) data are complicated by the presence of spectral overlap, low signal to noise and uncharacterized signal contributions. In this study, it is shown that an automated data analysis method can be used to generate metabolite images from MRSI data obtained from human brain at TE = 25 ms and 1.5 T when optimized pulse sequences and a priori metabolite knowledge are used. The analysis approach made use of computer simulation methods to obtain a priori spectral information of the metabolites of interest and utilized a combination of parametric spectral modeling and non-parametric signal characterization for baseline fitting. This approach was applied to data from optimized PRESS-SI and multi-slice spin-echo SI acquisitions, for which sample spectra and metabolite images are shown.

Duke Scholars

Published In

Magn Reson Imaging

DOI

ISSN

0730-725X

Publication Date

November 2000

Volume

18

Issue

9

Start / End Page

1159 / 1165

Location

Netherlands

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Magnetic Resonance Imaging
  • Inositol
  • Humans
  • Glutamic Acid
  • Creatine
  • Computer Simulation
  • Choline
  • Brain
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Soher, B. J., Vermathen, P., Schuff, N., Wiedermann, D., Meyerhoff, D. J., Weiner, M. W., & Maudsley, A. A. (2000). Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis. Magn Reson Imaging, 18(9), 1159–1165. https://doi.org/10.1016/s0730-725x(00)00212-5
Soher, B. J., P. Vermathen, N. Schuff, D. Wiedermann, D. J. Meyerhoff, M. W. Weiner, and A. A. Maudsley. “Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis.Magn Reson Imaging 18, no. 9 (November 2000): 1159–65. https://doi.org/10.1016/s0730-725x(00)00212-5.
Soher BJ, Vermathen P, Schuff N, Wiedermann D, Meyerhoff DJ, Weiner MW, et al. Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis. Magn Reson Imaging. 2000 Nov;18(9):1159–65.
Soher, B. J., et al. “Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis.Magn Reson Imaging, vol. 18, no. 9, Nov. 2000, pp. 1159–65. Pubmed, doi:10.1016/s0730-725x(00)00212-5.
Soher BJ, Vermathen P, Schuff N, Wiedermann D, Meyerhoff DJ, Weiner MW, Maudsley AA. Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis. Magn Reson Imaging. 2000 Nov;18(9):1159–1165.
Journal cover image

Published In

Magn Reson Imaging

DOI

ISSN

0730-725X

Publication Date

November 2000

Volume

18

Issue

9

Start / End Page

1159 / 1165

Location

Netherlands

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Magnetic Resonance Imaging
  • Inositol
  • Humans
  • Glutamic Acid
  • Creatine
  • Computer Simulation
  • Choline
  • Brain