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Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models.

Publication ,  Journal Article
Zhu, X-P; Du, A-T; Jahng, G-H; Soher, BJ; Maudsley, AA; Weiner, MW; Schuff, N
Published in: Magn Reson Med
September 2003

A new method, based on a deformable shape-intensity model (DSM), was developed to improve the signal-to-noise ratio (SNR) of multidimensional magnetic resonance spectroscopic imaging (MRSI) data sets without affecting spectral lineshapes and linewidths. Improvements with DSM, compared to digital filters using conventional signal apodization, were demonstrated on both simulated and experimental in vivo (1)H MRS images from 22 cognitively normal (CN) elderly subjects and 25 patients with Alzheimer's disease (AD). Simulated MRSI data showed that DSM achieved superior noise suppression compared to a matched apodization filter. Experimental MRSI data showed that SNR could be increased 2.1-fold with DSM without distorting spectral resolution, thus maintaining all spectral features of the raw, unfiltered data. In conclusion, DSM should be used to achieve high SNR in reconstructing MRSI data.

Duke Scholars

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

September 2003

Volume

50

Issue

3

Start / End Page

474 / 482

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Models, Theoretical
  • Male
  • Magnetic Resonance Spectroscopy
  • Image Processing, Computer-Assisted
  • Humans
  • Female
  • Computer Simulation
  • Brain Chemistry
  • Analysis of Variance
 

Citation

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MLA
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Zhu, X.-P., Du, A.-T., Jahng, G.-H., Soher, B. J., Maudsley, A. A., Weiner, M. W., & Schuff, N. (2003). Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models. Magn Reson Med, 50(3), 474–482. https://doi.org/10.1002/mrm.10572
Zhu, Xiao-Ping, An-Tao Du, Geon-Ho Jahng, Brian J. Soher, Andrew A. Maudsley, Michael W. Weiner, and Norbert Schuff. “Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models.Magn Reson Med 50, no. 3 (September 2003): 474–82. https://doi.org/10.1002/mrm.10572.
Zhu X-P, Du A-T, Jahng G-H, Soher BJ, Maudsley AA, Weiner MW, et al. Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models. Magn Reson Med. 2003 Sep;50(3):474–82.
Zhu, Xiao-Ping, et al. “Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models.Magn Reson Med, vol. 50, no. 3, Sept. 2003, pp. 474–82. Pubmed, doi:10.1002/mrm.10572.
Zhu X-P, Du A-T, Jahng G-H, Soher BJ, Maudsley AA, Weiner MW, Schuff N. Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models. Magn Reson Med. 2003 Sep;50(3):474–482.
Journal cover image

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

September 2003

Volume

50

Issue

3

Start / End Page

474 / 482

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Models, Theoretical
  • Male
  • Magnetic Resonance Spectroscopy
  • Image Processing, Computer-Assisted
  • Humans
  • Female
  • Computer Simulation
  • Brain Chemistry
  • Analysis of Variance