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Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis.

Publication ,  Journal Article
Ebel, A; Soher, BJ; Maudsley, AA
Published in: Magn Reson Med
December 2001

For many clinical applications of proton MR spectroscopic imaging (MRSI) of the brain, diagnostic assessment is limited by insufficient coverage provided by single- or multislice acquisition methods as well as by the use of volume preselection methods. Additionally, traditional spectral analysis methods may limit the operator to detailed analysis of only a few selected brain regions. It is therefore highly desirable to use a fully 3D approach, combined with spectral analysis procedures that enable automated assessment of 3D metabolite distributions over the whole brain. In this study, a 3D echo-planar MRSI technique has been implemented without volume preselection to provide sufficient spatial resolution with maximum coverage of the brain. Using MRSI acquisitions in normal subjects at 1.5T and a fully automated spectral analysis procedure, an assessment of the resultant spectral quality and the extent of viable data in human brain was carried out. The analysis found that 69% of brain voxels were obtained with acceptable spectral quality at TE = 135 ms, and 52% at TE = 25 ms. Most of the rejected voxels were located near the sinuses or temporal bones and demonstrated poor B0 homogeneity and additional regions were affected by stronger lipid contamination at TE = 25 ms.

Duke Scholars

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

December 2001

Volume

46

Issue

6

Start / End Page

1072 / 1078

Location

United States

Related Subject Headings

  • Signal Processing, Computer-Assisted
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Imaging, Three-Dimensional
  • Humans
  • Echo-Planar Imaging
  • Brain
  • 4003 Biomedical engineering
  • 0903 Biomedical Engineering
 

Citation

APA
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ICMJE
MLA
NLM
Ebel, A., Soher, B. J., & Maudsley, A. A. (2001). Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis. Magn Reson Med, 46(6), 1072–1078. https://doi.org/10.1002/mrm.1301
Ebel, A., B. J. Soher, and A. A. Maudsley. “Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis.Magn Reson Med 46, no. 6 (December 2001): 1072–78. https://doi.org/10.1002/mrm.1301.
Ebel A, Soher BJ, Maudsley AA. Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis. Magn Reson Med. 2001 Dec;46(6):1072–8.
Ebel, A., et al. “Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis.Magn Reson Med, vol. 46, no. 6, Dec. 2001, pp. 1072–78. Pubmed, doi:10.1002/mrm.1301.
Ebel A, Soher BJ, Maudsley AA. Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis. Magn Reson Med. 2001 Dec;46(6):1072–1078.
Journal cover image

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

December 2001

Volume

46

Issue

6

Start / End Page

1072 / 1078

Location

United States

Related Subject Headings

  • Signal Processing, Computer-Assisted
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Imaging, Three-Dimensional
  • Humans
  • Echo-Planar Imaging
  • Brain
  • 4003 Biomedical engineering
  • 0903 Biomedical Engineering