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Comparison of functional MR and H2 15O positron emission tomography in stimulation of the primary visual cortex.

Publication ,  Journal Article
Kraut, MA; Marenco, S; Soher, BJ; Wong, DF; Bryan, RN
Published in: AJNR Am J Neuroradiol
1995

PURPOSE: To locate spoiled gradient-echo functional MR signal changes in relation to brain parenchyma. METHODS: The region of the primary visual cortex was evaluated using functional MR and H2 15O positron emission tomography in each of six male subjects who were being visually stimulated by means of red light-emitting diode flash goggles. RESULTS: The positron emission tomography technique demonstrated substantially greater relative signal change with visual stimulation than did the functional MR technique. Furthermore, the functional MR signal changes were concentrated in loci around the periphery of brain parenchyma exhibiting increased radiotracer activity, as opposed to being collocated. CONCLUSIONS: Signal changes found using functional MR based on gradient-echo techniques reflect primarily phenomena occurring within small veins and underrepresent activity intrinsic to brain parenchyma, thus introducing potential inaccuracies in locating regions of activated brain tissue. Positron emission tomography, however, directly measures changes in metabolically related activity within the parenchyma.

Duke Scholars

Published In

AJNR Am J Neuroradiol

ISSN

0195-6108

Publication Date

1995

Volume

16

Issue

10

Start / End Page

2101 / 2107

Location

United States

Related Subject Headings

  • Visual Perception
  • Visual Cortex
  • Tomography, Emission-Computed
  • Regional Blood Flow
  • Reference Values
  • Photic Stimulation
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
 

Citation

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MLA
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Kraut, M. A., Marenco, S., Soher, B. J., Wong, D. F., & Bryan, R. N. (1995). Comparison of functional MR and H2 15O positron emission tomography in stimulation of the primary visual cortex. AJNR Am J Neuroradiol, 16(10), 2101–2107.
Kraut, M. A., S. Marenco, B. J. Soher, D. F. Wong, and R. N. Bryan. “Comparison of functional MR and H2 15O positron emission tomography in stimulation of the primary visual cortex.AJNR Am J Neuroradiol 16, no. 10 (1995): 2101–7.
Kraut MA, Marenco S, Soher BJ, Wong DF, Bryan RN. Comparison of functional MR and H2 15O positron emission tomography in stimulation of the primary visual cortex. AJNR Am J Neuroradiol. 1995;16(10):2101–7.
Kraut, M. A., et al. “Comparison of functional MR and H2 15O positron emission tomography in stimulation of the primary visual cortex.AJNR Am J Neuroradiol, vol. 16, no. 10, 1995, pp. 2101–07.
Kraut MA, Marenco S, Soher BJ, Wong DF, Bryan RN. Comparison of functional MR and H2 15O positron emission tomography in stimulation of the primary visual cortex. AJNR Am J Neuroradiol. 1995;16(10):2101–2107.

Published In

AJNR Am J Neuroradiol

ISSN

0195-6108

Publication Date

1995

Volume

16

Issue

10

Start / End Page

2101 / 2107

Location

United States

Related Subject Headings

  • Visual Perception
  • Visual Cortex
  • Tomography, Emission-Computed
  • Regional Blood Flow
  • Reference Values
  • Photic Stimulation
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging