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Representation of strong baseline contributions in 1H MR spectra.

Publication ,  Journal Article
Soher, BJ; Young, K; Maudsley, AA
Published in: Magn Reson Med
June 2001

A comparison is made between two optimization procedures and two data models for automated analysis of in vivo proton MR spectra of brain, typical of that obtained using MR spectroscopic imaging at 1.5 Tesla. First, a shift invariant wavelet filter is presented that provides improved performance over a conventional wavelet filter method for characterizing smoothly varying baseline signals. Next, two spectral fitting methods are described: an iterative spectral analysis method that alternates between optimizing a parametric description of metabolite signals and nonparametric characterization of baseline contributions, and a single-pass method that optimizes a complete spectral and baseline model. Both methods are evaluated using wavelet and spline models of the baseline function. Results are shown for Monte Carlo simulations of data representative of both long and short TE, in vivo 1H acquisitions.

Duke Scholars

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

June 2001

Volume

45

Issue

6

Start / End Page

966 / 972

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Protons
  • Nuclear Medicine & Medical Imaging
  • Monte Carlo Method
  • Magnetic Resonance Spectroscopy
  • Lipid Metabolism
  • Image Processing, Computer-Assisted
  • Humans
  • Energy Metabolism
  • Computer Simulation
 

Citation

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ICMJE
MLA
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Soher, B. J., Young, K., & Maudsley, A. A. (2001). Representation of strong baseline contributions in 1H MR spectra. Magn Reson Med, 45(6), 966–972. https://doi.org/10.1002/mrm.1129
Soher, B. J., K. Young, and A. A. Maudsley. “Representation of strong baseline contributions in 1H MR spectra.Magn Reson Med 45, no. 6 (June 2001): 966–72. https://doi.org/10.1002/mrm.1129.
Soher BJ, Young K, Maudsley AA. Representation of strong baseline contributions in 1H MR spectra. Magn Reson Med. 2001 Jun;45(6):966–72.
Soher, B. J., et al. “Representation of strong baseline contributions in 1H MR spectra.Magn Reson Med, vol. 45, no. 6, June 2001, pp. 966–72. Pubmed, doi:10.1002/mrm.1129.
Soher BJ, Young K, Maudsley AA. Representation of strong baseline contributions in 1H MR spectra. Magn Reson Med. 2001 Jun;45(6):966–972.
Journal cover image

Published In

Magn Reson Med

DOI

ISSN

0740-3194

Publication Date

June 2001

Volume

45

Issue

6

Start / End Page

966 / 972

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Protons
  • Nuclear Medicine & Medical Imaging
  • Monte Carlo Method
  • Magnetic Resonance Spectroscopy
  • Lipid Metabolism
  • Image Processing, Computer-Assisted
  • Humans
  • Energy Metabolism
  • Computer Simulation