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Using a latent variable approach to inform gender and racial/ethnic differences in cocaine dependence: a National Drug Abuse Treatment Clinical Trials Network study.

Publication ,  Journal Article
Wu, L-T; Pan, J-J; Blazer, DG; Tai, B; Stitzer, ML; Woody, GE
Published in: J Subst Abuse Treat
June 2010

This study applies a latent variable approach to examine gender and racial/ethnic differences in cocaine dependence, to determine the presence of differential item functioning (DIF) or item-response bias to diagnostic questions of cocaine dependence, and to explore the effects of DIF on the predictor analysis of cocaine dependence. The analysis sample included 682 cocaine users enrolled in two national multisite studies of the National Drug Abuse Treatment Clinical Trials Network (CTN). Participants were recruited from 14 community-based substance abuse treatment programs associated with the CTN, including 6 methadone and 8 outpatient nonmethadone programs. Factor and multiple indicators-multiple causes (MIMIC) procedures evaluated the latent continuum of cocaine dependence and its correlates. MIMIC analysis showed that men exhibited lower odds of cocaine dependence than women (regression coefficient, beta = -0.34), controlling for the effects of DIF, years of cocaine use, addiction treatment history, comorbid drug dependence diagnoses, and treatment setting. There were no racial/ethnic differences in cocaine dependence; however, DIF by race/ethnicity was noted. Within the context of multiple community-based addiction treatment settings, women were more likely than men to exhibit cocaine dependence. Addiction treatment research needs to further evaluate gender-related differences in drug dependence in treatment entry and to investigate how these differences may affect study participation, retention, and treatment response to better serve this population.

Duke Scholars

Published In

J Subst Abuse Treat

DOI

EISSN

1873-6483

Publication Date

June 2010

Volume

38 Suppl 1

Start / End Page

S70 / S79

Location

United States

Related Subject Headings

  • United States
  • Substance Abuse Treatment Centers
  • Substance Abuse
  • Sex Factors
  • Racial Groups
  • National Institute on Drug Abuse (U.S.)
  • Narcotics
  • Methadone
  • Male
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wu, L.-T., Pan, J.-J., Blazer, D. G., Tai, B., Stitzer, M. L., & Woody, G. E. (2010). Using a latent variable approach to inform gender and racial/ethnic differences in cocaine dependence: a National Drug Abuse Treatment Clinical Trials Network study. J Subst Abuse Treat, 38 Suppl 1, S70–S79. https://doi.org/10.1016/j.jsat.2009.12.011
Wu, Li-Tzy, Jeng-Jong Pan, Dan G. Blazer, Betty Tai, Maxine L. Stitzer, and George E. Woody. “Using a latent variable approach to inform gender and racial/ethnic differences in cocaine dependence: a National Drug Abuse Treatment Clinical Trials Network study.J Subst Abuse Treat 38 Suppl 1 (June 2010): S70–79. https://doi.org/10.1016/j.jsat.2009.12.011.
Wu, Li-Tzy, et al. “Using a latent variable approach to inform gender and racial/ethnic differences in cocaine dependence: a National Drug Abuse Treatment Clinical Trials Network study.J Subst Abuse Treat, vol. 38 Suppl 1, June 2010, pp. S70–79. Pubmed, doi:10.1016/j.jsat.2009.12.011.
Journal cover image

Published In

J Subst Abuse Treat

DOI

EISSN

1873-6483

Publication Date

June 2010

Volume

38 Suppl 1

Start / End Page

S70 / S79

Location

United States

Related Subject Headings

  • United States
  • Substance Abuse Treatment Centers
  • Substance Abuse
  • Sex Factors
  • Racial Groups
  • National Institute on Drug Abuse (U.S.)
  • Narcotics
  • Methadone
  • Male
  • Humans