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A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group.

Publication ,  Journal Article
Lance, RS; Freidrichs, PA; Kane, C; Powell, CR; Pulos, E; Moul, JW; McLeod, DG; Cornum, RL; Brantley Thrasher J,
Published in: BJU Int
January 2001

OBJECTIVE: To review and compare the outcome of patients undergoing radical retropubic prostatectomy (RRP) or radical perineal prostatectomy (RPP) for clinically localized prostate cancer. PATIENTS AND METHODS: From 1988 to 1997, 1382 men who were treated by RRP and 316 by RPP were identified from databases of the Uniformed Services Urology Research Group. The following variables were assessed; age, race, prostate-specific antigen (PSA) level before surgery, clinical stage, biopsy Gleason sum, estimated blood loss (EBL), margin-positive rate, pathological stage, biochemical recurrence rate, short and long-term complication rates, impotence and incontinence rates. To eliminate selection bias, the analysis was concentrated on pairs of patients matched by race, preoperative PSA level, clinical stage and biopsy Gleason sum. RESULTS: In the 190 matched patients there were no significant differences between the RRP and RPP groups in either organ-confined (57% vs 55%), margin-positive (39% vs 43%), or biochemical recurrence rates (12.9% vs 17.6% at a mean follow-up of 47.1 vs 42.9 months), respectively. The mean EBL was 1575 mL in the RRP group and 802 mL in the RPP group (P < 0.001). The only significant difference in complication rates was a higher incidence of rectal injury in the RPP group (4.9%) than in the RRP group (none, P < 0.05). CONCLUSIONS: In similar populations of patients, RPP offers equivalent organ-confined, margin-positive and biochemical recurrence rates to RRP, while causing significantly less blood loss.

Duke Scholars

Published In

BJU Int

DOI

ISSN

1464-4096

Publication Date

January 2001

Volume

87

Issue

1

Start / End Page

61 / 65

Location

England

Related Subject Headings

  • Urology & Nephrology
  • Treatment Outcome
  • Prostatic Neoplasms
  • Prostatectomy
  • Prostate-Specific Antigen
  • Neoplasm Recurrence, Local
  • Middle Aged
  • Male
  • Humans
  • Disease-Free Survival
 

Citation

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Lance, R. S., Freidrichs, P. A., Kane, C., Powell, C. R., Pulos, E., Moul, J. W., … Brantley Thrasher J, . (2001). A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group. BJU Int, 87(1), 61–65. https://doi.org/10.1046/j.1464-410x.2001.00023.x
Lance, R. S., P. A. Freidrichs, C. Kane, C. R. Powell, E. Pulos, J. W. Moul, D. G. McLeod, R. L. Cornum, and R. L. Brantley Thrasher J. “A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group.BJU Int 87, no. 1 (January 2001): 61–65. https://doi.org/10.1046/j.1464-410x.2001.00023.x.
Lance RS, Freidrichs PA, Kane C, Powell CR, Pulos E, Moul JW, et al. A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group. BJU Int. 2001 Jan;87(1):61–5.
Lance, R. S., et al. “A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group.BJU Int, vol. 87, no. 1, Jan. 2001, pp. 61–65. Pubmed, doi:10.1046/j.1464-410x.2001.00023.x.
Lance RS, Freidrichs PA, Kane C, Powell CR, Pulos E, Moul JW, McLeod DG, Cornum RL, Brantley Thrasher J. A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group. BJU Int. 2001 Jan;87(1):61–65.
Journal cover image

Published In

BJU Int

DOI

ISSN

1464-4096

Publication Date

January 2001

Volume

87

Issue

1

Start / End Page

61 / 65

Location

England

Related Subject Headings

  • Urology & Nephrology
  • Treatment Outcome
  • Prostatic Neoplasms
  • Prostatectomy
  • Prostate-Specific Antigen
  • Neoplasm Recurrence, Local
  • Middle Aged
  • Male
  • Humans
  • Disease-Free Survival